She played the role of Madame Queen on the Old Time Radio show, "Amos N Andy." She also continued the role in the TV series.
Lillian portrayed the family maid Birdie Lee Coggins on NBC Radio's "The Great Gildersleeve" (1941-1954).
She is the younger sister of actress Amanda Randolph and the mother of Barbara Randolph.
Recent showings of the Tom and Jerry cartoons have had Lillian Randolph's original voice of Mammy-Two-Shoes dubbed and replaced with that of voice actress June Foray.