Lisa Edelstein: The show is a medical drama with a twist, the lead [Laurie] is this brilliant, incredible doctor with this amazing talent, but really he has no interest in talking to people. Plus he's addicted to painkillers, which just adds fuel to the fire. House is very CSI-like in that it dives into the human body and gives viewers a tour of the body from the inside -- a look at the veins and the heart... It's dark yet it's funny. It's very intelligently written, sort of like a medical West Wing.