In 2011, Loretta won an Emmy Award for Outstanding Guest Actress in a Drama Series playing Adele Webber on Grey's Anatomy.
In 2002 she was nominated at the Image Awards for Outstanding Actress in a Drama Series for the TV series Boston Public.
In 2003 and 2004 she won the Image Award for Outstanding Supporting Actress in a Drama Series for Boston Public.
In 2005 she was nominated at the Image Awards for Outstanding Supporting Actress in a Motion Picture for the movie Woman Thou Art Loosed.
She was nominated at the 2007 Image Awards for Outstanding Actress in a Television Movie, Mini-Series or Dramatic Special for the tv movie Life Is Not a Fairytale: The Fantasia Barrino Story.
In 2000 at the Black Reel Awards she was nominated for Network/Cable - Best Supporting Actress for Funny Valentine.
In 2005 at the Black Movie Awards she was nominated for Outstanding Performance by an Actress in a Supporting Role for the movie Crash.
In 1971 she graduated with a BA from the University of Houston.
In April 2001 she was engaged to financial analyst Glenn Marshall.
Starred in The Lifetime Original Movie The Fantasia Barrino Story: Life is Not a Fairy Tale as Fantasia's Grandmother Addie Collins.
Loretta Devine (When asked about being recognized in public): I can basically go anywhere I want. Sometimes, people are shocked to see me in a place like Costco. They go, "What you doing in Costco?"
Loretta Devine: (When asked what her secret to keeping her career going) I have no idea. If I knew it, I would try and sell it, I could tell you. I love it so much, I love doing it so much, I think it goes on the screen and you can see that, I hope. That's part of what it is.
Loretta Devine (speaking about her cameo role in Dreamgirls): At first, I had such mixed feelings because they didn't want to pay me anything, and it was like "Come on."
Loretta Devine (when asked about her work with David E. Kelly:I absolutely fell in love with him when I was doing Boston Public. He's such an unusual man, and he used to be drive by and say, "Loretta, you're going to be in love with a midget next week." [laughs] And I'd be like, "David!" And he'd say, "You don't believe me? Wait until you see this scene."