In 1980, Lou published his first book entitled The Kitchen Quarterback through Parkin Printing. The book is subtitled Basics for the Beginning Football Fan.
In 1989, Lou published his second book entitled The Fighting Spirit: A Championship Season at Notre Dame through Simon & Schuster. The book was written with John Heisler.
In 1998, Lou published his third book entitled Winning Every Day through Collins Business. The book is subtitled The Game Plan for Success.
In 2006, Lou published his fourth book entitled Wins, Losses, and Lessons: An Autobiography through William Morrow.
In 2007, Lou published his fifth book entitled A Teen's Game Plan for Life through Sorin Books.
Lou is a member of the Augusta National Golf Club, home of the The Masters Tournament.
Lou was the head coach at the University of South Carolina for six seasons (1999-2005). He compiled an overall record of 33-37 and led the Gamecocks to the Outback Bowl at the conclusion both the 2000 and 2001 seasons. South Carolina won both games, defeating Ohio State each time by scores of 24-7 in 2000 and 31-28 in 2001.
In 1988, Lou led the Notre Dame Fighting Irish to the National Championship with a 12-0 record. Notre Dame defeated West Virginia 34-21 in the Fiesta Bowl to cap their perfect season.
Lou was the head coach at the University of Notre Dame for 11 seasons (1986-1996). He compiled an overall record of 100-30-2 and led the Fighting Irish to nine consecutive bowl games from 1987 through 1995. His teams had a record of 5-4 in the their bowl games.
Lou was the head coach at the University of Minnesota for two seasons (1984-1985). He compiled an overall record of 10-12 and led the Golden Gophers to the Independence Bowl at the conclusion of the 1985 season. Minnesota won the game, defeating Clemson 20-13.
Lou was the head coach at the University of Arkansas for seven seasons (1977-1983). He compiled an overall record of 60-21-2 and led the Razorbacks to bowl games in six of his seven seasons there. His teams were 3-2-1 in their bowl games.
In 1976, Lou coached the National Football League's New York Jets. He resigned with one game remaining in the season after going 3–10.
Lou was the head coach at North Carolina State for four season (1972-75). He compiled an overall record of 33-12-3 and led the Wolfpack to a bowl game in each season. His teams had a bowl record of 2-0-1.
Lou married to Beth Barcus of East Liverpool, Ohio on July 22, 1961. Lou and Beth are the parents of four children.
Lou was elected into the College Football Hall of Fame in 2008.
Lou's first head coaching job was at the College of William & Mary in Williamsburg, Virginia. He coached there for three seasons (1969-71), compiling an over-all record of 13-19 and led the team to the Tangerine Bowl, which they lost 40-12 to Toledo, at the conclusion of the 1970 season.
Lou: It's better to be patient in a car than to be a patient in a hospital.
Lou: If you really want to feel wealthy, focus on the things that money can't buy: health, friends and freedom.
Lou: If you are bored with life, if you don't get up every morning with a burning desire to do things - you don't have enough goals.
Lou: The problem with having a sense of humor is often that people you use it on aren't in a very good mood.
Lou: On this team, we're all united in a common goal: to keep my job.
Lou: I think everyone should experience defeat at least once during their career. You learn a lot from it.
Lou: I can't believe that God put us on this earth to be ordinary.
Lou: A lifetime contract for a coach means if you're ahead in the third quarter and moving the ball, they can't fire you.
Lou: Do right. Do your best. Treat others as you want to be treated.
(when formally announced his retirement as head football coach at the University of South Carolina in 2004)
Lou: I'm thankful for the opportunity. I have been truly blessed to be around our coaches and our players. I don't know where I'm going to go, I don't know what I'm going to do. I have faith in the Lord to let him lead me. As long as my family's with me, everything else will be okay. But I do feel confident leaving here that the football program is on a firm foundation.
(when asked about his favorite physical attribute about himself)
Lou: None. I'm small, weak and unattractive.
(announcing his retirement as head football coach at the University of South Carolina)
Lou: It's always with mixed emotions whenever you leave somewhere. It's never a good time.
(upon having a statue dedicated to him by the University of Notre Dame)
Lou: I think it's as high an honor as I could ever receive. But it's a tribute to the players, the administration, the athletic directors. One person doesn't do that. That takes so many people. I'm humbled by it.
(after Notre Dame defeated West Virginia to win the 1988 national championship)
Lou: You dream about it, but I never thought it would happen to me. I never thought I would coach a national championship team. It still hasn't sunk in.
Lou: The man who complains about the way the ball bounces is likely the one who dropped it.
Lou: Life is ten percent what happens to you and ninety percent how you respond to it.
(upon learning of his election into the College Football Hall of Fame)
Lou: I could never thank the people of the Ohio Valley enough for instilling in me the morals and values. I just hope my induction will serve as an example to persevere. I've been fired and ridiculed and downgraded. That's all part of life. You just continue to move on.