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Luis was nominated for a SAG Award in 1998 for the movie
Boogie Nights. The category was Outstanding Performance by a Cast in a Theatrical Motion Picture. He was also nominated for a SAG award in 2000 for the film
Magnolia in the same category. In 2001, he won the SAG Award for Outstanding Performance by a Cast in a Theatrical Motion Picture for
Traffic.
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Luis is of Puerto Rican descent.
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Luis prefers his first name pronounced "Loo-ee".
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Luis had a featured part in his high school play of Bye Bye Birdie.
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Luis performed street theater while in college.
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Luis graduated from City College of New York.
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Luis has been married since 1985, and has five children. Four adopted, and one of their own.
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Luis made his television debut in an episode of Miami Vice.
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Luis was a social worker before he was an actor.
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Luis won Best Supporting Actor at the Imagen Foundation Awards, for his role in Punch-Drunk Love.
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Luis was the only actor with a major role to appear in both Carlito's Way, and its prequel Carlito's Way: Rise to Power.
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Luis voiced the character of "Ricardo Diaz" in Grand Theft Auto: Vice City, and then reprised his role again in Grand Theft Auto: Vice City Stories.
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Luis' favorite actor is Marlon Brando.
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Luis is regularly cast in films by Brian DePalma, Paul Thomas Anderson, and Steven Soderberg.
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Luis owns the ranch Wild Orchard Stables.
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Luis is 5' 7 1/2" (1.71 m).
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He often plays a cop or a villains' sidekick.