She was member of the Circle Repertory Theatre (now-defunct) in New York City.
She received a BA in English and speech at University of Illinois Champaign-Urbana.
She was nominated for the 1981 Tony for Featured Actress (Musical) for her role in Tintypes.
She won the 1997 Tony for Featured Actress (Play) for her role in An American Daughter.
Lynne's son is actor Kevin Thigpen.
The late Lynne Thigpen has an elementary school in Joliet, Illinois named after her. The Lynne Thigpen Elementary School.
The District also had a funeral for Thigpen's character.