A biological weapon is used in a failed assassination attempt, sending John, Natalie and Malcolm on a frantic race to thwart a domestic terrorist group's plans to deploy a virus on a greater scale.moreless
An aging mobster sends three Wesen men out on a quest to win his daughter's hand... by killing the man who killed his son. Meanwhile, Nick and Adalind continue adjusting to life together at the fortress, Rosalee receives a letter from someone she knew in her addict days, and Renard is asked to support a mayoral candidate.moreless
Stefan talks to Damon about a concern he has with Elena, and Damon has no option but to help Stefan try to get to the bottom of the issue. The brothers visit New Orleans, hoping to find anyone who remembers the events of their last visit in 1942, including Charlotte, a former love interest of Damon's. Elena, Caroline, and Bonnie organize a girls' night while Damon and Stefan are out of town, and Elena shares some surprising information. Hayley's convinces Tyler to confront one of Klaus' hybrids, Kimberly, but the confrontation quickly becomes violent. Finally, Damon must make a heartbreaking decision.moreless
Hank's latest case involves a boy with asthma. Paige's secret comes to light and Divya goes on a date.