Season 1 concludes with Brian dealing with a stunning betrayal as he and the FBI race to stop an NZT-enabled Sands and his associates from orchestrating an international incident of evil. Meanwhile, Brian also experiences devastating side effects when his NZT immunity begins to wear off.moreless
The FBI's worst nightmare comes true when NZT floods the streets of New York City and threatens to become a national epidemic. As efforts are made to stop it from spreading, a joint manhunt is launched to find the lab producing the drug; at the same time, Brian struggles to adjust to his new reality when he lacks the resources to continue searching for Piper.moreless
Rebecca takes NZT for the first time to see justice for her father's murder. To ensure success of his new plan, Sands makes a risky move against Brian.
Brian's double life unravels when Senator Morra makes contact just as Brian's placed under 24-hour surveillance by the FBI following his rogue trip to Russia. And the possibility of his connection to Morra being exposed seems even greater when Mike and Ike reveal to an already suspicious Rebecca that Brian had an off-book interaction with Morra's henchman Sands.moreless
With his closest relationships imploding, Brian goes rogue from the FBI and heads to Russia to find the only person who can help him cut ties once and for all with Senator Eddie Morra. As he tracks down a former Morra associate-turned-adversary who possesses an alternative NZT vaccine, Rebecca comes closer to discovering Brian's secret.moreless
Brian and Rebecca are placed under quarantine together after they are exposed to an unknown substance during an investigation into a citywide blackout. Already feeling too close for comfort, trust issues arise when Brian is caught using his stash of NZT.moreless
Brian is covertly enlisted by Senator Morra's henchman Sands, who finds that his dangerous past has caught up with him and he needs Brian's help dealing with a life-or-death threat. Meanwhile, it's up to Rachel to cover for her brother when the FBI comes calling about another case.moreless
Sparks fly between Brian and an undercover FBI agent as they race to finish a case before her real identity is exposed. Meanwhile, Sands makes a surprising move to end Rebecca's investigation into Senator Morra.moreless
Brian embarks on his first FBI field assignment when he travels to Quantico to lend his skills to the bureau unit that catches serial killers. Meanwhile, Rebecca comes closer to discovering Senator Morra's connection to NZT.moreless
Senator Edward Morra is targeted by a would-be assassin, and Brian is ordered to sabotage the FBI's investigation into the murder attempt in order to prevent exposing the senator's connection to NZT.
An internal investigation is launched after Casey Rooks and his SWAT team are caught stealing NZT pills from a stolen batch they helped recover.
Boyle comes to the aid of a former military buddy who's being charged with murder, and he asks Brian for help proving that his friend's prosthetic arm was hacked to commit the crime. Elsewhere, Brian's dad is adamant that his son stop working for the FBI.moreless
Brian makes a deal with Naz to get his own personal work "headquarters," but to score the space he has to capture the FBI's 10 Most Wanted criminals in just two weeks. Meanwhile, Brian's relationship with his father becomes strained under the secretive nature of his new life working for the Bureau.moreless
Brian tangles with real pirates who are holding a girl against her will. Brian and Rebecca work to clear Naz of treason charges, only to discover that there's a family secret she is keeping from the FBI.moreless
Brian fakes being sick in order to take a day off from working with the FBI. Unfortunately, the plan backfires when the CIA abducts him from home to "borrow" his NZT-enhanced skills for what turns out to be a dangerous black ops mission that ends up spiraling out of control.moreless
Brian's physical and mental health begin to deteriorate again, but Edward Morra is demanding a high price in exchange for another inoculation. Brian secretly looks for an alternate cure for himself while he works with Rebecca outside FBI parameters to find the creators of NZT.moreless
Brian discovers a shocking secret about Rebecca's late father, but worries that telling her will land him in legal trouble; at the same time, he ends up meddling in her personal life while learning self-defense from her secret FBI boyfriend.moreless
Loyalties are tested when Sands demands that Brian steal the FBI's secret files on NZT. When her estranged father dies, Agent Harris is conflicted after learning what he left her.
When Harris and Boyle, helped by Brian, investigate the murder of a retired FBI agent, they find a link to the elusive head of a notorious drug cartel. When Brian reconnects with an old flame, he worries she's only interested in the NZT version of him.moreless
Brian puts his new job with the FBI in jeopardy when he disobeys orders to stay out of an investigation into the murder of a renowned journalist.
Trapped in the past, Abbie tries to convince Ichabod that they are future partners while trying to stop Katrina from assuring the Horseman's victory.
Ichabod and Abbie try to stop Henry's scheme to use a mystic bell to create a new cult of witches. However, they learn that he has an unexpected ally. Meanwhile, Irving comes after Jenny.moreless
Ichabod and Abbie find a new series of tunnels beneath Sleepy Hollow and have an encounter with an old friend of Ichabod's. Meanwhile, Katrina receives a visit from Henry, and Jenny receives a visit from Irving.moreless
Solomon Kent, a warlock who set off the Salem Witch Trials to protect himself, seeks out a Grimoire that will give him the power to undo the mistake in his past that turned him into a warlock. Meanwhile, Irving approaches Abbie, while Henry contemplates his past and decides on his future.moreless
Nick's godmother, the woman who raised him after his parents died, asks for his helping stealing a mystic artifact. He reluctantly agrees, putting him at odds with Abbie, Ichabod, and Jenny. Meanwhile, Irving is cleared of the charges against him but Cynthia still has concerns.moreless
Ichabod and Katrina attend the Sleepy Hollow Historical Soiree and become embroiled in a murder. Meanwhile, Abbie receives an unexpected visit.
While questioning their purpose now that Moloch is dead, Ichabod and Abbie discover that a group of demons have escaped from Purgatory... as has an angel, Orion. Meanwhile, Katrina offers Abraham the chance to restore his humanity.moreless
The End of Days draws nigh, and Ichabod and Abbie capture Abraham in the hopes of learning where they can find Moloch and Henry. However, Abraham reveals that the Sword of Methuselah can only be used at a terrible cost.moreless
Abbie and Jenny investigate strange suicides at Tarrytown that may be connected to their mother Lori. Meanwhile, Katrina realizes the nature of the baby and prepares to banish it back to Purgatory.