Pellegrino was a serious contender for the character of Castiel in the fourth season of Supernatural before Eric Kripke chose to cast Misha Collins in the role. Mark instead landed the role of Lucifer for the 5th season of the show.
In June 2006, Mark was featured in an interview article in the Quarterly Newsletter of Playhouse West for his appearance in the film The Number 23, which starred fellow PW alumnus Jim Carrey.
Mark has been involved with the Notre Dame Workshop and Bob Hoover.
In 1989, Mark appeared as himself in the Hulk Hogan tribute video, Hulkamania 4.
Pellegrino was directed by Playhouse West founder and co-teacher Jeff Goldblum in Little Surprises. Also, he acted with Goldblum in the 1997 film The Lost World: Jurassic Park.
Along with TV actors Nestor Carbonell (Lost), Wentworth Miller (Prison Break), Kathryn Morris (Cold Case) among others, Mark is featured in the "Playhouse West Students At Work" section of Playhouse West School's website.
In between auditioning for roles in 1991, Pellegrino worked for a while as canvasser for the California chapter of NARAL Pro-Choice America.
Mark, who was featured in Lost's season five finale along with series regulars Naveen Andrews (Sayid) and Elizabeth Mitchell (Juliet), also appeared with the two actors in the "The Price" episode of the short-lived 2001 ABC series The Beast.
Mark engages in several forms of martial arts such as Karate, Judo, Ju-Jitsu, kickboxing, and professional Thai boxing.
His first appearance in a feature film was in the 1987 Whoopi Goldberg movie, Fatal Beauty.
Pellegrino underwent actors' training at North Hollywood Playhouse West, where he himself taught students some time after.
Film, Video, and TV Movie Credits:
• An American Affair (2009) as Graham Caswell
• The Thacker Case (2008) as Ron Pebble
• Disappearing in America (2008) as Bodyguard
• The Last Days of Limbo (2008) as Cardinal Reynolds
• Suspect (2007) (TV) as Jack Lambroso
• Caffeine (2006) as Tom
• Spartan (2004) as Convict
• NYPD 2069 (2004) (TV)
• Zelda (2003) as Reginald
• Moving Alan (2003) as Alan Kennard
• Ronnie (2002) as Keith Schwann
• Astronauts (2002) (TV) as Hollywood
• Treading Water (2002) as The Actor
• Fault Lines (2001)
• Monsters (2001) as Sally Spinelli
• Something Else (2000) (V) as Julian
• Certain Guys (2000) as Cal
• Lost in the Pershing Point Hotel (2000) as Tripper
• Clubland (1999) as Lipton T
• Honest Injun (1999)
• Movies Kill (1997)
• The Lost World: Jurassic Park (1997) (uncredited) as Tourist #6
• Born Into Exile (1997) (TV) as Walter, Owner of Eatery
• Soul of the Avenger (1997)
• The Temple of Phenomenal Things (1997) as Dodd
• Macon County Jail (1997) as Dan Oldum
• The Cherokee Kid (1996) (TV) as Frank Bonner
• Dick Richards (1996) as The Boytoy
• For Life or Death (1996)
• Little Surprises (1995) (TV) as Jack
• Knight Rider 2010 (1994) (TV) as Robert Lee
• Bank Robber (1993) as Motorcycle Cop
• Class of '61 (1993) (TV) as Skinner
• Midnight Witness (1993) as Patterson
• Inside Out (1991) (V) as Jack - segment "Doubletalk"
• Blood and Concrete (1991) as Bart
• Night Life (1989) as Allen Patumbo
• What Price Victory (1988) (TV)
Along with the cast of Capote, Pellegrino was nominated for a Screen Actors Guild Award in the category Outstanding Performance by a Cast in a Motion Picture in 2006.
His theatrical credits include 9-11, Minor Holiday, Italian-American Reconciliation, Winter into Spring, Welcome Home Soldier, Lou Gehrig Didn't Die of Cancer, Of Mice and Men, and The Exonerated.
Mark is 6'1" (1.85 m). He has natural blonde hair.
Mark Pellegrino: With experience, I learned to either do what a director asks me to fully, or politely sit down and say, 'Here's what I think.' You end up being more satisfied with your work when you do that.
Mark Pellegrino: (on his admiration for "The Number 23" co-star Jim Carrey and their similarity on both being perfectionists) ...someone who makes 20 or 30 million a movie deals with the same insecurities, is fallible and can be unsure about what's happening. Even if you're older and wiser, you can still tend to idealize a person and think they can do anything. Not that you are reassured at their lack of anything, but at their humanity.
Mark Pellegrino: (advice to acting students) What I've loved in certain actors like Jeff Bridges, Naomi Watts, and Philip Hoffman is something I'd like to transmit to the students; it's a childlike willfulness to do and play. You develop a technique to the point it becomes a part of you, but you must never cling to a technique. In the end you just let go and do. I don't care how good a technician you are, if you can't play, you're done.
Mark Pellegrino: Acting is always on a case-by-case basis, with the only thing governing you is trying to get to the truth.
Mark Pellegrino: People will treat you like you're invisible if that's the way you treat yourself.