Muse Watson attended Louisiana Tech on a music stipend for two years before transferring to Berea College, Berea, Kentucky, where he performed for the first time on stage as Petruchio in "Taming of the Shrew". During and after his years at Berea, he worked in outdoor dramas, dinner theaters, and small repertory groups. His theater credits include Hamlet in "Hamlet", Stanley in "A Streetcar Naned Desire", Pale in "Burn This", Cervantes in "Man of La Mancha", and directed "Ain't MisBehavin". In 1989, with a new commitment to film, Muse began pursuing roles in feature film. By 2004, he had appeared in 40 feature films.