The series finale of Fraiser finds Martin and Ronee on the verge of matrimony, and Niles and Daphne preparing for labor. Meanwhile, Frasier prepares for his career in a new city.
Niles prepares to undergo heart bypass surgery. Daphne is beside herself, and everyone relives some hospital memories.
Daphne returns with a surprising explanation for her recent weight gain. Meanwhile, Roz writes a children's book based on a story her mother used to tell her.
Daphne becomes agitated and restless the week before her wedding to Donny. Meanwhile, Niles struggles with second thoughts about his relationship with Mel.
Daphne wrestles with her feelings for Niles on the evening of her wedding to Donny.
Frasier's old love, Diane Chambers, comes to Seattle for the grand opening of her play about the "losers" at Cheers and their hopeless obsession with "Mary Anne."