Saffron was turned away from playing a role on the BBC series Grange Hill because she was too tall.
She has a brother named Santi.
In 2008, Saffron was nominated, along with her Boston Legal castmates, for a Screen Actors Guild Award for Outstanding Ensemble in a Drama Series.
She was nominated for "Favorite Actress - Newcomer" in the Blockbuster Entertainment Awards in 2000 for her role in Deep Blue Sea.
Her theatrical credits include Le Silence de la Mer, Night Sky, Some Girls, The Earthly Paradise, The Powerbook, Two Lips in Different Red and Urban Myth.
Saffron has modeled for the following names and brands: Alice Temperley, Bella Freud, Edna Ronay, Mulberry, Nicole Farhi, Chanel, Calvin Klein, Karl Lagerfeld, Romeo Gigli, Viviene Westwood and Yves Saint Laurent.
Saffron revealed that she is bisexual in a 1999 interview with Film Unlimited.
In 2004, Saffron was the vice-president of the National Civil Rights Movement, a political group which campaigns for racial justice and equal human rights for ethnic minorities.
Her nickname is Saff. When she was a kid, Saffron insisted friends to call her Mandy. She wanted to become a rapper and believed she it would be better to have a more common name.
Saffron made her film debut in a 1990 documentary called The Body Beautiful where she played herself.
Saffron has written two articles for the New Statesman entitled "My Baguette with Václav" (July 2006) and "A Date with Two Gores" (October 2007).
Being the daughter of politically active, socialist-feminist parents, she earned her childhood pocket money by selling the Socialist Worker. Furthermore, she attended marches and rallies after school and allegedly even shared her home with miners on strike.
She is 6' (1.83 m) tall.
Saffron: When I was younger, I was more in a hurry to get somewhere. I was very aware of mortality. In the last couple of years, I've felt less pressured that way: I've been very much in the present. I feel very peaceful about where I am. I love working, but I don't want that to be my only sense of identity.
Saffron: Getting sacked by Woody Allen was a low point. But he wrote a very sweet letter, saying that - are you ready for this? - I had 'a purity the camera couldn't hide!
Saffron: We're all influenced and partly formed by where we come from, whether its Clacton or Chile.
Saffron: Location work has its charms, and can seem glamorous on the outside, but I think living at home and having the stability of a home life once you've finished work is very underrated!
Saffron: I like working on stage because there's something very immediate about it, that interaction with an audience where you immediately hear their reaction, or feel them, whether they're with you.
Saffron: I don't find sex on its own that interesting in a film but I find the two, when they're interwoven, to be interesting.
Saffron: You've got to keep your principles - I want a career of some longevity. I'm really interested in women's rights, that may sound unappealingly feminist, but I am.
Saffron: And there's the whole lie about women's bodies that makes me angry. I barely met anyone who wasn't on some kind of strange ingestion of coffee and cigarettes and, invariably, cocaine, or something. A lot of that was about being very skinny, and for some people that has a lasting effect.
Saffron: I like that sensation of the years passing, and then of being able to look back, almost as if it were someone in a different cycle of their life.
Saffron: (on the world of modeling) It's only when you get far away from it that you begin to see things you couldn't at the time. Just the idea that that world is deeply troubling and corrupting and, of course, full of glitter.
Saffron: (on being a celebrity in Hollywood) You suddenly realize the way the system works there. It's formulaic, it's also incredibly powerful, and it can affect your life in quite a big way.
Saffron: I like being in love, but loving is what is crucial to me. Loving is the reason to live.
Saffron: When your life is as precious as all our lives are, then it needs to be kept precious and looked after and treated well. And that is not something we should be sharing with a wider audience.
Saffron: (on the birth of her step-brother) I was on the cusp of womanhood, so it was both visceral and personally significant.
Saffron: I don't think who I sleep with is of any interest to anyone. I have a beautiful life, and it is precious and it is private. I am terribly happy. That is all.