A BBC Fact File says that she's famous for, "Being that face in British films that you recognise, but can never put a name to."
Played Charlotte in Dirty Filthy Love which won 2005 RTS Drama Award for Best Single Drama.
Has worked with Rufus Sewell on two BBC dramas.
She won Best Comedy Actress at the 2004 Newport Beach International Film Festival for her work in the movie American Cousins.
Shirley is the oldest actor to play a student in the Harry Potter films. She was 35 when she made her first appearance as Moaning Myrtle.
Won the award for Best Actress at the 2003 Bordeaux International Festival of Women in Cinema for her role in Wilbur Wants to Kill Himself.
Starred in 2005 movie Frozen.
She is currently working on a movie called I Really Hate My Job with Neve Campbell.
She claims to have seen a ghost standing at the bottom of her bed when she was in Russia.
Shirley graduated from drama school in 1986.
She played the lead role of Katherine in a BBC updating of Shakespeare's Taming of the Shrew as part of their Shakespeare Retold mini series.
Shirley studied at Kirkaldy Technical College.
Shirley has worked with famous actor Robert Carlyle on two occasions; in the television series Hamish Macbeth and in the movie Trainspotting.
She appeared on the talent show Opportunity Knocks not for acting but for singing.
She worked on stage as a member of England's National Theatre Company.
Shirley is the eldest of three sisters.
In 2003 for her work in 24 Hour Party People, Shirley was nominated for the British Supporting Actress of the Year award by the London Film Critics Circle.
She had a supporting role in the movie '24 Hour Party People' in which she played Lindsay Wilson
Shirley studied at the Guildhall School of Music and Drama in London.
Shirley plays Bridget's friend Jude in the movie Bridget Jones' Diary.
Shirley makes an appearance in 1996 movie Trainspotting.
Shirley: It's dressing up and playing around and being daft.
Shirley: I daydream all the time, and I like that quality. You suddenly find yourself somewhere and you wonder, how did I get in this room? That happens to me all the time, every day!