Sprague was among Inside TV magazine's 50 Hottest New Faces on Television in 2005. She was also christened TV's Sizzling New Star in 2007 by Netscape Celebrity.
Being raised in Manchester, Massachusetts, Sprague grew up with a steady diet of lobster, fish, clam chowder, roast beef sandwiches, chicken, broccoli, and rice.
Sprague: Secretly, I'm a real big nerd. I'd rather stay home and play Scrabble than go to a Hollywood party, any day of the week. And I love reading about history and watching the Discovery Channel.
Sprague: (advice for girls on staying healthy) Some girls need to remember that in this country, we only seem to see extremes. People are either anorexic, or they're obese. The fact of the matter is, you should be in the middle. If you're hungry, you're still growing, and you need to eat. I was lucky I was raised by parents who gave me a lot of sense of self and a lot of confidence in myself.