She got the role of the Borg Queen on Star Trek: Voyager because Alice Krige (who played the role in the movie Star Trek: First Contact) refused to reprise her role.
She was in the 1994 film 'When a Man loves a Woman' which starred Andy Garcia and Meg Ryan. She played Janet. She was also in the 2005 film 'Hello' which also starred Eric Stoltz.
Susanna Thompson: (about Don Bellisario's writing) It's very smart writing. He's brilliant that way, because you need to give these people a backstory. You need to have a history. You need to help them to show up as real people. And that's how the writers and the creators can help the actors do that.
Susanna Thompson(about working with a parrot on 'Dragonfly'): The only way I could work with the animals was to embrace "Emily's" love of animals, and go there because I'm very unsure of animals. I was not raised with animals. As long as I felt her heart with me, then I was fine with it.
Susanna Thompson(about being the Borg Queen on 'Star Trek'): I do realize that. Next Generation was one of my husband's favorite shows when it was first on, for its stories and caliber of acting. When I got a small part on Star Trek: The Next Generation, I could go home and just say, "Here's your gift. I did it, now leave me alone." But it unfolded into another Next Generation appearance, and into a Star Trek: Deep Space Nine, and then into Voyager. I had no idea it would be the first step on a path into Star Trek history.