In 2008, Zach appeared in a series of web commercials for Absolut vodka, with their skits paying homage to the '80s show The Golden Girls.
Galifianakis prefers mixing up the work that he does such as doing some stand-up comedy and making small films that he himself wrote.
He used to have a pet cat named Mr. Stevenson after the British singer-songwriter Cat Stevens.
Into the Wild director Sean Penn got interested in casting Zach for the film after seeing him in Out Cold, a snowboarding movie Zach was in which Penn's son kept watching over and over.
He owns a 60-acre farm in North Carolina which he dreams of converting into a writers' retreat. He spends some time there when he's not working in Los Angeles, California.
His uncle Nick Galifianakis is a former member of the U.S. Congress and represented North Carolina from 1967-1973. He also went up against Jesse Helms for the Senate seat in 1972.
In 2006, Zach released a single called "Come Over and Get It (Up in 'Dem Guts)", a comedic rap/hip-hop/dance song.
Galifianakis, who was a series regular as Davis on Tru Calling, said that he hated being on the show.
Zach is of Greek descent and belongs to the Greek Orthodox faith.
TV Movie, Video, and Film Credits:
• G-Force (2009) as Ben
• Gigantic (2008) as Homeless Guy
• What Happens in Vegas (2008) as Dave the Bear
• Have Tig at Your Party (2008) (V)
• The Pity Card (2006) as Zach
• Zach & Avery of Fergus (2004) as Homeless Man
• Stella Shorts 1998-2002 (2002) (V) as Santa
• Next! (2002) (TV)
• Flushed (1999) as Pathetic Guy
• The King and Me (1999) as Pizza Boy
Zach made a short film with fellow comedian Brian Posehn.
Zach is 5' 8" (1.73 m) tall. He has often been seen in his shows and movies with a full beard, which he named Shelly.
He is friends with comedian Patton Oswalt. Oswalt was the one who invited him to join The Comedians of Comedy tour, which helped Zach to be more recognized by the public.
He can play the piano. Zach incorporates his musical talents in his stand-up comedy gigs.
In February 2008, Zach joined Will Ferrell's Funny or Die college tour. He also once performed on a tour called the Comedians of Comedy.
His favorite movie is Garfield while one of Zach's favorite shows is All in the Family.
Zach: Wherever there's something that people don't feel comfortable talking about, that's where the good jokes are... A bad comic follows his audience, catering to whatever they want; a good comic will always lead.
Zach: I love to do shows in unlikely places, because the audience's expectations are less fixed.
Zach: My brother was torturous, I guess, but in a funny way. He used to say to me, 'I'm giving you a gag order,' then stuff his dirty underpants into my mouth. He used to drag me stark naked across the lawn, then hold me up by my ankles for the passing cars to see.
Zach: (on his sudden success; in a 2009 interview) If I were 26 and this was happening, it would be all great, and I would probably buy like 17 Dodge Vipers. But right now it's just a major inconvenience.
Zach: (recalling a time when he did "Late World with Zach") I knew from day one, when the VH1 guys came in and said, 'Don't make fun of Cher, don't make fun of Sheryl Crow.' Whatever their rotation was at the time. I was like, 'Well, this isn't a good marriage.'
Zach: When I first got to L.A., I had a pretty good setup. I convinced a mechanic to let me live in an Audi that was waiting to get fixed. I'd drive it around for a while, then it would break down and have to be fixed again, which meant I got to keep it for a little while longer. It was kind of an everybody-wins situation, except for the poor lady who was waiting for her Audi.
Zach: (recounting his first time doing stand-up comedy) It was in the back of a hamburger joint in Times Square. I did a joke about not wanting to sleep on a girl's futon because it rhymed with crouton. I do not recall anyone laughing.
Zach: I am not really into porn. I have always wanted to go to a table read for a porn though. If I were to pick a genre it would have to be kitty porn (pornography with cats only) - often confused with you-know-what.
Zach: (excerpt from his bio on his website) I feel that living your life in contradiction keeps one confused and happy... It makes me laugh when people miscommunicate. I like walking over bridges and hate Donald Trump or anything like him. The entertainment business is both poison and honey.
Zach: I'm not cynical when it comes to things that are important. I'm cynical about pop culture and all that horseshit.
Zach: (in a 2007 interview) I was talking to my mom the other day, and she called me a weirdo. It was the first time I'd ever heard her say that, and I told her that I thought she was weird. So we got that out of the way. I think that I could be in porno, but as long as I was flying my parents around, they wouldn't really care. [Laughs.]
Zach: I never really did the club stuff; I'm really kind of a wimp that way. I just stay mostly in Los Angeles and perform in front of people wearing ironic T-shirts. That or a few goth chicks.
Zach: When you look like I do, it's hard to get a table for one at Chuck E. Cheese.
Zach: You know you're an alcoholic when the bartender knows your name... and you've never been to that bar before.
Zach: I like to go to really bad movies, during their sixth week, and there's only one other person in the theatre, and I like to sit right next to them. And they're like, 'excuse me?', and I'm like, 'Shhh, I can't hear Keanu.'