As Holmes and Watson work a standard murder investigation, they encounter MI-6 and find the case has international and political inferences. Watson re-examines her relationships with Mycroft and Sherlock.
Holmes and Watson chase the source of a lethal toxin after a pickpocket dies of anthrax poisoning.
Holmes and Watson investigate when a presumed dead serial killer looks as if he's killing again.
Holmes and Watson investigate when an influential cancer researcher is murdered. They must figure out if his new cutting-edge invention played any part in his death. Detective Bell is given clearance to resume field work.moreless
Holmes and Watson are called in to consult when a woman, who was thought murdered by her husband years ago, appears now to be a victim of a kidnapping after her husband receives a ransom demand. Holmes and Watson are eager for Lestrade to leave the brownstone but he doesn't seem inclined to do so.moreless
Tensions rise when Sherlock and Watson are teamed up with Lestrade to find the person responsible for a bombing.
When a up-and-coming ballerina is murdered, Sherlock is called in to solve the case. Watson tries to find a homeless veteran after his friend reports him as kidnapped.
As Watson peruses one of Holme's cold cases, she figures out that a rare prehistoric fossil is tied to the unsolved murder. Sherlock is in uncharted territories as concerns his duties as a sobriety sponsor.moreless
While Holmes tries to make amends with Detective Bell, he and Watson look into the mafia's association with a body found in a barrel.
Moriarty is brought in to consult on a kidnapping case, bringing Holmes and Watson face to face with their former adversary. Detective Bell persists in his efforts to make a full recovery.
Holmes and Watson set out to determine which client killed a hedge fund manager running a Ponzi scheme. Sherlock considers becoming a sponsor for a recovering addict.
An official police inquiry into one of Sherlock's investigations puts his and Watson's future with the NYPD on the line.
It's the NYPD versus Holmes and Watson when the two sleuths uncover a cold case serial killer.
Mycroft shows up in New York to ask Holmes and Watson to solve a case concerning his former fiancée. Mycroft and Joan's relationship is a source of contention with Sherlock.
As Holmes and Watson investigate the murder of a financial consulting company's CEO, a mysterious woman from Holmes' past surfaces as a suspect.
Watson and Holmes search for the civil contractor responsible for leaking classified information but soon find themselves targeted by cyber activists. Joan decides to sign up at an online dating service.
Holmes and Watson investigate the murder of a well-respected mathematician and look into the guarded equation he was trying to decipher. Watson is at a loss when a former patient's son asks her for a loan.moreless
Holmes and Watson head to London for an unsolved mystery investigation and to look up his former mentor, Gareth Lestrade. Sherlock joins up with his estranged brother, Mycroft, who discloses some secrets.
A group of protesters breaks into the NYPD precinct after the police are suspected of killing an unarmed man. Mac and Flack find themselves caught up in the chaos as the team makes a fast move to try and solve the case. On the personal side, Mac contemplates his future with Christine.moreless
At Valentine's Day the CSIs get a taste of both the sweetest and the sourest that life can offer as they work on three twisted tales of love gone wrong.
A couple of graffiti artists, who vandalize their district using the tag 'Murderer', will find their sign a very close reality when a body is dumped at their feet.
The CSIs lead an investigation after the body of a masked man found at the bottom of a notorious skyscraper adds to the mysterious count of deaths that form part of the history of the building. Meanwhile, Jo runs into a stranger with an unexpected link to her past while enjoying a day off.moreless
Two men are found dead with a common feature: both have been killed using unconventional methods. Meanwhile, $1 million anonymous checks are left around the city by someone known as the Guardian Angel.moreless