In the Season 2 finale, Thackery ignores Zinberg's advice at Mt. Sinai and undertakes a risky, alternative course of action; Cornelia confronts Henry about the family business; Barrow's actions at the hospital construction site are called into question; Gallinger ponders a job opportunity; and Cleary steadfastly refuses to give up on Harriet.moreless
Thackery attempts a new cure in the inebriation ward; Brockhurst demands his "girls" be returned; Gallinger and his wife's relationship and Bertie's relationship with Genevieve go off in surprising directions. Later, Cornelia shows evidence of the company's wrongdoing to Henry; Barrow's marriage troubles come to a head; and Thackery performs plastic surgery on Abby.moreless
Thackery tries to steady his nerves as he prepares to separate conjoined twins before a packed audience, while Cornelia receives a surprise gift from her father-in-law and attends a charity ball for the new Knick. Later, Barrow rids himself of a threat; Opal puts a damper on the Robertsons' good mood; Algernon receives long-overdue recognition in the surgical theater, but complications arise.moreless
Bertie is faced with a quandary at Mt. Sinai, which leads to him take matters into his own hands and enlist help from Algernon; Thackery considers using hypnosis, while taking an interest in conjoined twins. Later, Lucy lobbies Henry for an invite to a gala; Cornelia visits the brother of a deceased immigrant who had ties to Speight; Gallinger has an unwelcome dinner guest; Barrow checks out a new home for Junia; and Harriet agrees to make some changes.moreless
A subway explosion sends a flood of patients to the Knick; while being pursued by Henry, Lucy heeds advice from one of Ping Wu's girls. Later, a troubled addict makes an ideal test case for Thackery's theory on addiction; Bertie submits his adrenalin findings to Zinberg; Cornelia uncovers a clue about Speight's death; Barrow pays off a debt; Genevieve charms the Chickerings; and Harriet becomes a boardinghouse pariah.moreless
Edwards aids Thackery in testing out a new hypothesis. Genevieve Everidge works a story on a Thackery competitor. Cornelia is upset about the limits of Phillip's sympathies. Barrow must deal with a new adversary at Tammany Hall. While at a class reunion, a discussion of eugenics grabs Gallinger's attention.moreless
Dr. Thackery makes a move to return to The Knick, which the board frowns upon; Cornelia gets Cleary to do a dirty job, but it comes with a cost; Robertson makes a push for a new subway initiative; Barrow drives up construction costs; and Lucy receives a surprise visitor from home.moreless
With The Knick preparing to move uptown, Edwards lobbies the hospital board to be appointed permanent head of surgery. Even with his suspension lifted, Gallinger refuses to return as Edwards' subordinate, so he heads to Cromartie Hospital in hopes of getting Thackery to return to work. Lucy tries to make amends with Bertie but has little success. Cleary looks for ways to make extra money. Ping Wu demands regular medical checkups for his prostitutes. Speight makes an effort to trace the origins of a new plague. Cornelia feeds a quarantined neighborhood in San Francisco.moreless
Watson and Holmes investigate the murder of a bioengineer whose death may be linked to a drug cartel. Meanwhile, Kitty searches for a runaway teen; and Joan makes a major life decision but worries it will have a negative impact on Sherlock.moreless
Robertson must come up with hush money to cover up a late-night crime at the Knick; a desperate Thackery looks to Lucy to obtain his drugs; and Eleanor's erratic behavior concerns Gallinger.
Racial tensions ramp up on the street and at the Knick when a black man stabs a cop defending his wife; Everett finds a changed operating room on his return to work; and Barrow has concerns about Junia's safety. Meanwhile, Edwards' ingenuity and skills impress Cornelia.moreless
Thackery and Bertie test a new operating-room procedure; Cornelia is second-guessing her impending nuptials; and Thackery considers a salesman's intriguing pitch. Meanwhile, Everett contemplates how to help Eleanor overcome her grief; and Barrow wheels and deals over some used merchandise.moreless
During surgery, Thackery's hand is forced by Algernon, which angers Eleanor; a recovering Abigail regrets her involvement with Thackery; and Sister Harriet and Cleary make a couple of deals. Meanwhile, Bertie receives a scolding from his physician father who is unhappy with his son's career path; and Lucy becomes privy to Thackery's secrets.moreless
As Thackery directs Gallinger and Chickering to conduct experiments on pigs, he ponders whether to operate on a former flame. Barrow goes to great lengths to repay an obligation and get back a missing tooth. Edwards takes out his frustrations at a local bar. Robertson's request for administering treatment to a typhoid fever patient are considered at long last.moreless
Incensed over the problems with the hospital's new electrical system, Thackery instructs hospital superintendent Barrow to get him more cadavers to enable his team to investigate new surgical procedures. As the rate of patient deaths increase, Edwards proffers a technique he learned in France. A typhoid fever epidemic is tackled by Robertson while Thackery confides in Elkins. Edwards figures out another way to carry out his job.moreless
Blair must make the big choice between Dan or Chuck; Lola reflects on Nate asking her to move in with him; Lily makes a final decision regarding her marriage.
Serena must be Blair's double when Blair finds herself needed in multiple places at once; Chuck enlists the help of both Ivy & Lola in order to carry out a revenge plot; Nate sorts out his future with Diana Payne.moreless
Diana and Jack have a deep dark secret; Chuck investigates to find out what is really going on; Dan gets an offer to study abroad in Rome.
Blair and Dan throw out a big party for them to come out as a couple, Gossip Girl may ruin Lola's biggest dream; Serena and Diana have a face-off.
Serena is determined to turn Lola into the next "it-girl" of the Upper West Side, starting with trying to persuade Lola to model at a Kiki de Montparnasse Lingerie show. Meanwhile, Chuck reached out to Blair for advice about his past. Diana Payne's return to The Spectator starts a power struggle with Nat for control, while Lola reacts with jealousy; but everything is not what it appears. It is discovered that Chuck paid Blair's dowry to get rid of Louis' family. Also, Rufus and Lily have a falling out after Lily goes behind Rufus' back to play a simply scheme to remove Ivy from their penthouse.moreless
Chuck thanks his uncle Jack for saving his life. Blair and Dan try to take their relationship to the next level. Lily has tries to adapt to living in Brooklyn while Ivy adapts to her new life on the Upper East Side. Serena takes on the role as Gossip Girl from the package Georgina left her.moreless