When Lance walks over Charlie while he is getting all of the lady's belongings from the burning building, you see Charlie's fur go completely one shade of light brown instead of his normal colors.
In the beginning, his copy of the Guardian Angel Rulebook is gold, though near the end, it's blue.
Itchy: Lance just saved you, Charlie! He's unbelievable!
Charlie: "Unbelievable". That's the word for him, alright!
Lance and Charlie sings: By the Book
Carface and Killer aren't in this episode.
This epsiode was released on home video with the episode "The Perfect Dog".
Charlie: See ya later, Lancenator!
This a reference to the song "See Ya Later Alligator", by the band Bill Haley and The Comets.
Otto: Very interesting...
This is a reference to the late comedian Arte Johnson, a regular on the seventies sketch show Rowan & Martin's Laugh In. Arte's most well-known sketch portrayed him as a german soldier, whose catchphrase was "Very interesting...", followed by either a comic observation or misinterpretation, or simply "but stupid!"
News Reporter: "...Number Ten, Burt Reynolds' hair piece!"
When Charlie goes out alone, upset because he thought everybody liked Lance more than him, he stops by a store with TVs in the window. The News reporter says that one of the top ten things Lance could save would be "Burt Reynolds' hair piece".
Burt Reynolds did the voice of Charlie Barkin in the first All Dogs Go To Heaven movie. In fact, that's what Charlie's middle name is based on. The B. is for Burt.