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While Lana tries to shut down Briarcliff for good, in the present Bloody Face's son continues his father's work.
Jude faces another threat to her life when a new inmate joins Briarcliff. Meanwhile, Grace turns increasingly distracted as her obsession with her alien abductors grows.
When Jude threatens to bring down Briarcliff, Howard takes extreme measures. Meanwhile, Grace gives Kit a message and Thredson receives a visitor.
While Arden concludes his experiments, Howard meets Mary Eunice's inner self and Kit has an unexpected reunion.
Lana receives startling news from Mary Eunice. Meanwhile, Arden sets out to learn what happened to Grace and Monsignor Howard takes on a true believer.
While a killer Santa stalks the sanitarium, Sister Jude battles Satan himself and Arden enters the Death Chute.
While Kit tries to reunite with Grace, Mary Eunice discovers that a dark force has invaded Briarcliff.
While Howard makes a deal with Arden that he may live to regret, a young girl is dropped off at Briarcliff. Meanwhile, the true identity of Bloody Face is revealed.
Bloody Mask's identity is revealed after Kit makes a confession. Meanwhile, Sister Jude learns about Arden's past and brings in a Nazi hunter to get the proof she needs to deal with the doctor and the threat he poses to her control.
While Kit learns the real reason that Grace is in Briarcliff, Arden must cope with a patient who claims to be Anne Frank... and can reveal his twisted past.
Kit, Grace, and Shelley plan to use a storm as a distraction to escape. Meanwhile, Sister Jude faces a ghost from her past and Arden begins to lose his nerve, while Lana finds an ally in Dr. Thredson.
The staff summon an exorcist to deal with a possessed farm boy, while Sister Jude's dark past is revealed and Lana and Grace plan an escape.
An insane asylum plays host to a deranged serial killer who stalks the borders between insanity and reality.