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When Daniel is looking at his parents through the glass door, we can see the reflection of the cameraman as the shot moves up.
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M.E. tells Rene she's known Colliar since she was 8 years old, but every other time they mentioned M.E. and Colliar knowing one another, they were 10.
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In "Three Hours a Week", M.E. claimed that the only thing about her book that was based in fact was the name Port Dixie. In "Where's the Justice in That?", the scene from the book that's being produced for the school play details the actual events of the day that M.E. and Rene met.
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M.E. reminds Colliar that Kelly is 10 weeks pregnant. But in "It's a Mother-Daughter Thing", M.E. told Rene she was 9 weeks pregnant and there is a month's difference between episodes. So Kelly should be between 13 and 14 weeks pregnant.
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When Rene first asks Donny's mother about his father, she said, "He's crazy.". Later, she states in court that his father was shot and killed four years earlier.
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When Rene and M.E. are mixing the alcohol together, M.E. asks Rene if she found any booze at her house. But they were AT Rene's house while they did it.
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M.E. tells Rene Rick got busted for making a bunch of 11 year olds do a Busby Berkley number in his pool. When this happened, it was the summer prior to this meaning the girls would have been 10 instead of 11.
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Catherine buys M.E. her first bra in this episode. However, in past episodes, we can tell she's wearing a bra by the lines in her clothes.
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When the boys start calling for Teresa, the girls want to know what the big deal is. Tully tells them it's because she had sex with her boyfriend, and M.E. and Rene act completely clueless, even though they started finding out about sex in "It's Who You Sleep With".
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When Teresa and her boyfriend are seen stepping out of his car, Rene exclaims "She's naked!" and M.E. responds "So's he! Is that what y'all look like?", even though we can see the waistband of the boyfriend's boxers. Previously, M.E. mentioned going down to the swimming hole to look at naked boys, so why would she be surprised when she saw Teresa's boyfriend?
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When M.E., Rene, Colliar, and Tully are at the fireworks stand, Tully takes TNT snaps and a box of matches out of his pocket, lights the snaps, and then throws them at Rene's feet. Snaps are just meant to be thrown on the ground to explode. Lighting the tips doesn't do anything.
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When Kelly comes home with her hair done up, she told M.E. that Ajoni's sister did it for her. Throughout the rest of the series, we never hear of her again, and we never see her.
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When Rene reminds M.E. of the time she made slow gin fist punch and they got drunk and were sick for days, she said it was in Grandma Otis' basement. But in "Nope" when we see it happen, they're at Rene's house.