I liked Kelsey Grammer in Frasier and Cheers. He will always be Frasier Crane to me. After 20 years of playing the same character in 2 shows, typecasting is bound to be a problem.
Overall it was a good show - its a typical sitcom. Grammer returns to his old studio in Pittsbugh (My home town - nice to see various places mentioned and a nice shot of the city skyline in the background of the news studio).
One of the characters was running around sweating so bad his shirt had huge stains under his arm pits - that was gross. Other than that it was a pretty good pilot. So far, its not as good as Cheers or Frasier, but it could grow on me over time.