Megan and Tommy attend her father's exhumation but it only yields more questions. Joan suggests Megan check out her father's patient files for a connection to his death.
An accused murder violently escapes from a transport van and soon the witness in his case is found dead. He heads straight to Megan pleading that he's being framed and didn't commit the murder. It's up to Megan to find the truth.
A plane crash in Philadelphia takes out the city's main power grid making it difficult for Megan and the rest of the team to conduct the necessary autopsies. While investigating the plane crash, Tommy and Riley are involved in a serious car accident.
Megan and Tommy must determine who killed a schizophrenic teenage girl at a mental institution. To make things interesting, a patient claims that the murderer really meant to kill her, and they are being stymied by the ward director.
An investment banker on trial for defrauding investors is kidnapped leaving court and later surfaces in a video as having been killed. Tommy and Adam have to determine if he faked his own death. Megan learns more about her father.
When Tommy is discovered at the scene of a young girl's murder, covered in blood, Megan is his only hope.
A woman's savage murder leads Megan and Tommy to a neighbor inflicted with rabies who bites Tommy and is diagnosed with rabies. Kate calls in the new health commissioner, Dr. Charles Stafford, to help Megan when a second case of rabies is discovered sans bite marks.
Kate begins to suspect that the handsome and mysterious Sergei, with whom she's having a tryst, may be involved in the death of a young Russian girl.
Working with Tommy on a vigilante killing, Megan meets up with a grief counselor who offers to help her deal with issues about her father's suicide.
The shooting death of a New York mobster's son creates a tense situation when the mobster threatens to find and kill the person responsible. Megan and the team must hurry to solve the case after one suspect is killed.
Megan and Tommy must separate out fact from fiction to determine if a child's murder was severe child abuse or something else.
While Kate comes under fire from D.A. Russell, Megan has cracked the case but can't tell her team. As long as the killer has Lacey, Megan must keep what she's learned to herself.
As Megan returns to work months after Peter's death, she is thrown together on a new case with a detective from her past. A serial killer is seeking out young war veterans but the case hits close to home for Megan when the killer takes Lacey hostage.