Brennan has Booth, Hannah, Hodgins and Angela over for dinner but they are interrupted by a case. They find a Caucasian female as the victim and she has the same ring as Brennan. They go back to lab and find a fracture to her temporal bone and signs of defensive wounds.
They find out the victim could have been a surgeon. Hannah finds her online and they discover she didn't have anyone to really miss her outside of work. The similarities between Lauren (the victim) and Brennan begin to become clear. They find out that Chris had feelings for her and her photo looks exactly like Brennan!
Brennan comes to the office at night at listens to Lauren's audio recordings and it is her voice...
Brennan asks Micah to help her with the case and find out that she was killed by a blow to the head but had been stabbed months ago. Sweets discovers Brennan looking into the case and decides that she is "over-identifying" with the victim.
Brennan and Booth go to talk to Dworsky, a patient's father. He said he had no hard feelings but also told them that Lauren has denied his son a heart that was a perfect match.
Brennan finds a flashlight that could be the murder weapon.
Hodgkins finds opiates in the tree and suggests that a drug dealer could have been involved. Brennan insists that Lauren could not have done drugs and Hannah suggests that she was given drugs before she was killed.
Brennan begins talking to the victim and asking her about the heroin. Micah calls a cab and tells Brennan she needs some rest. Sweets gives his take on who Lauren was. She had behaved irrationally and received "suicide by murder."
Brennan finds out that Lauren wants another heart for Dworsky's son from a child that lived in Woodland, where her body was found. She goes there and finds a reflector on the road. Booth saves Brennan from an oncoming car. Brennan discovers that bought the heroin and got hit by a car and struck her head on the reflector. The driver had buried her.
She says that she had never given Chris a chance and that was her one regret and begins to tie it into her own life. Booth says he loves Hannah and Brennan starts crying, saying that she missed her chance and that she has to adjust.