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This episode borrows heavily on elements from the classic 1948 film Key Largo.
Michael Lane is billed as Michael St. John in the ending credits.
The script of this episode is a reworked version of an episode of Maverick entitled Escape to Tampico.
The characters of Jim and Sally Mason are mistakenly billed as Jim and Sally Martin in the ending credits.
Blooper: In the dialogue of the episode it's stated that the Cotton Bowl is located in New Orleans. This is wrong. The Cotton Bowl is located in Dallas. The Sugar Bowl takes place in New Orleans.
This episode takes place in a state besides Louisiana because counties in that state are referred to as parishes and here the setting is called Midas County.
Goof: the character of Jimmy Joe Barteri is also referred to as Jimmy Joe Bartelli in the dialogue.
James Coburn's character mentions that he'll probably have to hide out in Cuba until the heat's off. Evidently, the writers weren't paying much attention to the political events in 1960 Cuba because the Communist Fidel Castro had just seized power there.
The Axeman of New Orleans was a real life serial killer who attacked at least 12 victims with an axelike object in the New Orleans area during 1918 and 1919. Not all of his victims died but he was never identified conclusively or apprehended.
By paying close attention to the complexions of the male guest stars in this episode, the viewer can figure out who the culprit is prior to the end of the show.
Rex's parent's names, Helen and Willard, are spoken for the only time in the series.
The impression that Andrew Duggan does in this episode is of classic actor Charles Boyer.
Mary Tyler Moore plays the missing woman in this episode but received no screen credit for her appearance, one of her first in television.
The impression that Andrew Duggan does is of actor Charles Laughton.