The Walkers bid farewell to Holly as she decides to move to New York to be with her daughter Rebecca. Surprisingly, Nora assists her in her move and the two women realize the share a unique bond. Many flashbacks of the extended Walker family's lives ensue.
Annie's ex-boyfriend saves Justin from being put on probation after Justin performed a risky procedure that saved a patient's life.
Saul makes amends with the man who transmitted the HIV virus to him, Jonathan (Richard Chamberlain). The two marvel on how gay men of their generation faced more obstacles than they do today, as evidenced by Kevin and Scotty's adoption of a teen girl. Said teen steals from her soon-to-be adoptive dads, and already the new parents are putting their parental skills to the test.
Kitty suddenly breaks things off with Seth and heads to Washington DC with Evan for a visit with Robert's ex-wife and his kids while she plans to work. Once there, Kitty seems upset and leaves Evan with Robert's ex wife and we're left guessing why.