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In order to release Anson's hold on Fiona, Michael plans on taking him down once and for all. Meanwhile, Pearce offers Michael a special mission: leading a team of operatives to capture a spy recruiter.
Michael wants to find out more about Anson's plans, but this requires the help of a former enemy. Meanwhile, an old friend contacts Jesse, asking him to help bring his diamond-smuggling employer to justice.
Michael must ask Anson for help after Sam's old friend Beatriz turns up in Miami with a hitman on her trail.
Michael runs point on a CIA rescue mission which involves a scientist kidnapped by an African warlord. Meanwhile, Sam and Jesse go undercover as microchip specialists but quickly get in over their heads.
When the life of one of Michael's childhood friends is taken by gang warfare, things get personal as he decides to team up with the victim's brother to entrap the gang in a weapons scheme.
Michael and Fiona go to Puerto Rico to kidnap a financial hacker whose software they need for Anson. However, things get complicated when some dangerous enemies are waiting for the hacker back in Miami. Meanwhile, Madeline gets some training from Sam and Jesse to be able to retrieve sensitive information from the police.moreless
Michael tries to clear his name of Max's murder by taking drastic action. Elsewhere, Larry resurfaces and insists Michael help him with a job
In order to catch a bioweapons specialist, Michael and Fiona go undercover at a South American resort. In the meantime, Sam and Jesse corner Max's killer.
When Jesse needs Michael's help with a security job, Michael joins a group of hijackers who wind up taking hostages at an airport.
Fiona and Jesse work together for a pharmaceuticals magnate, but soon realize that he is hiding something. Meanwhile, Michael and Sam take on a bomb-maker involved in Max's death.
Michael and Jesse go on an extraction mission on a Caribbean island but end up trapped there by mercenaries. Meanwhile, Fiona tries to get information out of an ex by doing a favor for him.
The CIA abandons Sam after he goes undercover with a heroin dealer while trying to recover a weapon. Meanwhile, Michael's CIA contact continues searching for Max's killer.
Picking up 6 months from where Season 4 left off, we follow Michael on a CIA Mission to find the last man on the list of people that burned him.