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Sarah Clarke (as Christine Chambers) is the second 24 alumnus to appear on Commander in Chief - Leslie Hope (as Melanie Blackston, in a recurring role) is the other. In fact this brings the show full circle for 24 viewers as this is the final episode while Leslie Hope made her first appearance in the first episode. To add to this Donald Sutherland, is the father of 24 lead Kiefer Sutherland and Henry Lennix has since landed a role on 24.
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It's unclear if this was intentional or not, but at one point during the President's birthday party near the end of the show, a short black woman walks up to her and wishes her a happy birthday. This looks startlingly like Michaëlle Jean, Canada's current Governor General.
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At one point, Jim, the President's Chief of Staff see's the President's aide, Vince, holding a bow and arrow. Jim says, "I'm betting this president can handle a bow and arrow." This comment is an inside joke as Geena Davis, who plays the President almost made the 2000 US Olympic Archery team in 1999.
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The current order for the succession of a President was established by The Presidential Succession Act of 1947, signed by President Harry Truman.
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Keaton became the second person to leave the Vice Presidency in the same presidential term. Mac had left the vice presidency to become President while Keaton resigned.
In real life the vice-presidency did become vacant twice in the same presidential term during the 1973-77 term. Congress had first approved Gerald R. Ford who ultimately became President, and then Nelson A Rockefeller who served out the rest of the term.
Unlike Ford and Rockefeller, Keaton being a Congress approved Vice President ended the vice-presidency without having to become President nor serving out the remainder of the term.
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Leslie Hope played Former Attorney General Melanie Blackston. She teamed up with Nathan Templeton against President Mackenzie Allen.
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Goof: Air Force One is shown landing in Orange County, but the only commercial airport in Orange County, California is John Wayne Airport, whose runways can not accommodate Boeing 747s (such as Air Force One). Presidents visiting Orange County normally land at Los Angeles International Airport (LAX), the nearest airport capable of handling a 747.
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It is revealed that President Mackenzie's code name is "Victory".
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Amy Calloway takes a copy of the Gettysburg Address from the Lincoln Bedroom of the White House.
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The submarine in the episode is an Ohio–Class Guided Missile Submarine (SSGN) named the USS Seattle. The name of the sub does not match actual Navy naming conventions. In the United States Navy, all but one Ohio–Class submarine are named after States (the other is named after a Navy hero). All submarines named after cities are Los Angeles–Class Attack Submarines (SSN).
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Polly Bergen, who begins her recurring role as the mother of the first woman President of the United States, has herself played the first female President in the 1964 movie comedy Kisses for My President.
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The book Vince removes from his box after Allen asks him to stay is entitled Finding a Job That Matches Your Personality.
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Goof: There is a flashback episode with President Bridges and VP Allen flying on Air Force One. However, for security reasons, the President and VP are not allowed to fly on the same plane.
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In Allen's governmental universe, the Senate has no part in Advising and Consenting on the choice of the Vice President. Apparently, they have given that power over to the House.
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Goof: The President is seeing her husband and kids off while standing in front of the White House and a major mountain range is visible in the distance. However, there are no mountain ranges in the immediate D.C. area.
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Horace is four minutes older than Rebecca.
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Goof: The President refers to F-15E's but the footage shows F-16's.
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San Pasqual is a fictitious country.
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In the credits, J. Scott Shonka is credited as Colonel Wesley, but in the episode he is wearing the silver leaf, which is the insignia for a lieutenant colonel. If he were a colonel, he should be wearing an eagle.
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Goof: In the credits, the general is credited as General Pollack, but in the scenes, his nameplate reads General Pollak.