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Warrick: I blew it.
Grissom: Yeah. But you're not the one who's paying for it.
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Detective Vega: You don't just spontaneously develop a fatal head wound.
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Detective Vega: Court documents Garret Kwan was suing you for sexual harassment.
Serena: Are you familiar with the term "spurious"?
Detective Vega: Are you familiar with the term "murder suspect"?
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(After he finds trophies that were stolen from Matt's house in Jacob's car)
Grissom: If this is evidence, it needs to be tagged and catalogued.
Warrick: This is the same guy who shot Matt's daughter in the head and he's walking around laughing at us!
Grissom: Can you prove that?
Warrick: What's this? I've been putting guys away like this for years and now that it matters it seems like you're holding me back here! (shows people from the lab overhearing Warrick yelling)
Grissom: The job, Warrick is to process evidence objectively and without prejudice.
Warrick: I'm so sick of hearing that. I've heard it a million times! I can't be a robot like you. I actually care about these people!
Grissom: You know what, you're not working on this case anymore. I'll have another assignment for you tomorrow.
Warrick: Keep it. (Warrick leaves angry and hits a mail cart on his way out)
Grissom (to everyone in the lab): Where were we?
Bobby: At a dead end
Grissom: Go back to work.
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Nick: You gotta get a girlfriend.
Archie: You first.
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Archie (to Nick about girl in a case): Oh Serina, you can defrag my hard drive any time.
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Greg: All work and no play makes Greg a dull boy.
Grissom: All play and no work makes Greg an unemployed boy.
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(after Nick takes Archie to a crime scene at a software company)
Greg: I thought we had a relationship! What are you doing taking Archie into the field instead of me?
Nick: Right tool for the right job, man. You have to understand the world you're investigating.
(Greg gives Nick a look)
Nick: Hey, Archie? What's that "Star Trek" episode with that guy and the forehead thingy and the time portal...?
Archie: In classic, TNG, DS9, Voyager or Enterprise?
Greg: Point taken.
Archie: Or were you thinking about Farscape?
Nick: I have no idea what you're talking about.