After years of pursuit and a countless number of murders, Langston comes face-to-face with serial killer Nate Haskell inside the house where his killing spree began.
Langston becomes more determined than ever to track down Nate Haskell, the notorious "Dick & Jane" killer, after discovering that he's kidnapped his ex-wife, Gloria.
Nick and Greg have a barn full of scattered body parts to piece together - without names or heads to identify them. Langston's old nemesis, Nate Haskell, is back in action and playing his usual game of five-level chess against the LVPD.
Langston and Sara investigate the strange case of Iona, a social worker whose own psychological fetish led to her death, while Nick and Brass try to find those responsible for the chilling suicide of a 17 year old girl, a victim of cyber bullying.
The CSIs start a frenzy of betting pools when it looks like they're about to hit The Cycle: a homicide, suicide, accidental death and natural death during one shift.
While investigating the murder of a convicted ex-cop, the CSIs stumble upon a list in his prison cell with names of several individuals he believed might have been his wife's true killer.
Jason McCann contacts Nick and says that he's in imminent danger. Langston has a courtroom war of nerves against serial killer Nate Haskell. A bomb tech disarms a bomb attached to Nick's house. But when he accompanies Nick, Catherine and Vartann to a warehouse with multiple booby-traps per square inch, Kip has to really earn his paycheck to find a safe way out for the CSI team.
Sara clashes with her mother-in-law and a woman from Gil's past when the CSIs investigate a car bombing tied to the faculty and students at a local college's Department of Deaf Cultural Studies.
The team discovers that a series of seemingly random deaths by homemade electric chairs are actually linked to a murderous miscarriage of justice seventy years ago.
The team tries to figure out who's responsible for the death of a hooker whose "death" photo was put on the Internet - first as a joke, and then for real.
The CSI team investigate the murder of a man whose daughter was killed five years ago, and the bizarre death of a young man who appears to have been killed by a T-Rex.
The CSI team investigates a murder at the home of Marta, a "level 5 hoarder" whose home is stacked high with possessions and garbage and more than one dead body.
The CSI team investigates a mad slasher who strikes without leaving a trace -- because he wears a form-fitting black latex suit that leaves not a molecule of evidence behind.
During the annual Blood Fest convention, shocking violence erupts between the "vampires" and the "werewolves", ancient rivals who cannot abide betrayal...
Hysteria ensues when a shark attacks a woman in the pool at a Las Vegas casino "day club," and the CSIs must determine if the killer is human or shark.
Ray Langston fights for his life after being stabbed by psychopath Nate Haskell, while the other CSIs try to catch an anti-government bomber who is responsible for a series of explosions at a funeral that they attended.