Sara and Greg become quarantined after entering a crime scene that is contaminated with a deadly pathogen.
The CSIs investigate a present-day crime with ties to a mob heist that occurred 25 years ago. Meanwhile, Brass has a decision to make when his daughter attempts suicide.
Russell is taken hostage after a teenager opens fire in a police station.
The CSIs investigate the murder of a rock and roll groupie and the disappearance of a prostitute that both have ties to a mysterious band.
The CSIs investigate the murders of an Elvis impersonator and a bird that are somewhat connected.
Nick and Greg investigate the death of a 16-year-old girl with ties to a brothel.
The CSIs investigate a car crash and are shocked to discover the victim is someone that they know.