This episode has a few sides that are not just notable, but exceptional to say the least.
First there is the Marisol. Let me as a guy start with the shallow part. Alana is one of the most beautiful women i have ever beheld. Of course, in this series she did get 'the curse'. Becoming the love intterest of the main star is like getting a 'red shirt' role in Star Trek. The producers desperately require a character like Horatio to be single and available. Hence... bye bye Marisol, and having a brother as a starplayer helps it all.
The deeper part here is that the story has more then one good twist. The main story is that someone we know will get hurt.... a lot. This and the involvement of a drug cartel makes this one hell of a ride.
As a cliffhanger, this is the best cliffhanger any CSI has ever produced, and i feel certain that we will see a lot more action before long.