Horatio and Speedle are called to the scene of a murder. While they are examining a blood trail, a man with a CSI jacket on is intently studying the scene as well. Suddenly, Speedle spots the man poking around the evidence. The man grabs a latex glove, covered in blood - an important piece of evidence - and makes a break for it.
After the man runs off, Speedle angrily confronts a police officer, Officer Everhart, assuming he must have let the man into the crime scene. Everhart tells Speedle he figured the man was a CSI because of his jacket. When the men examine the log sheet, they see that the man signed his name as Edmond Locard, who Speedle identifies as the founder of modern forensics. They've been had.
Yelina, Delko and Calleigh are called to the scene of another murder. A young woman's body has been found in a dumpster off Collins Street, where some ritzy Miami clubs are located. At first they assume she was a clubgoer, but when Calleigh notices her comfortable shoes don't match her outfit, they realize she was a bartender.
They trace her to a swanky bar that boasts a huge ant tank at its center. Apparently, customers like to eat the ants fried; some believe the ants are an aphrodisiac. The manager, Mark Hobbes, identifies the dead woman as Barbara Nance. Calleigh and Delko are suspicious of Hobbes, especially when they find a gun behind the bar - a gun Hobbes denied having.
They discover the DNA of Jen Kemp, another bartender, on the gun and bring her in for questioning. She claims to have pulled a gun on a customer who got a little too pushy, but she says she never fired it.
Meanwhile, Speedle has tracked down the man who stole his evidence, one Wally Shmagin. Rather than running again, Wally is impressed with the ease with which Speedle traced him. Speedle tells Wally he wants the latex glove back and threatens to have him charged with obstruction of justice. Rather than being scared, Wally is impressed - this is definite bragging material. Wally finally relinquishes the glove, which has been meticulously bagged and tagged. Speedle sighs and realizes he's stuck with Wally...