The crew of the Antares is threatened by a close solar flare. In the meantime, the mysterious element in Pod 4 sends out a siren call no one can resist.
While Goss is working on a plan to promote the mission in front of the eyes of the whole world, the Antares crew suffers from hallucinations that could interfere with his plan.
While getting closer to Venus, some crew members are confronted with memories of past actions and struggle with guilt. When one of them gets into a life-threatening situation, the team unites to save her.
The Antares crosses a point of no return and turning back to Earth is no longer an option. In the meantime, each of the crew members has to cope with a personal point of no return.
Personal and professional relationships get more intense on Earth and aboard the Antares. In the meantime, the Antares' crew undergoes cellular and psychological transformations which is caused by the unseen power behind the mission.
An unaccounted hatch failure puts Zoe's life at risk. Meanwhile, the new mission commander Ted Shaw is asked to visit the mysterious element in Storage Pod 4.
In 2052, four women and four men prepare to start the most ambitious exploration of the solar system in the history of mankind aboard the Antares. When two of the astronauts get sick, one of their alternates learns the true nature of the mission.