Simion: I want to walk like you, talk like you.
Simion: Thank you, little friend!
This the first appearance of Agent Honeydew, who become Monkey's girlfriend for the next few Monkey episodes.
Simion's voice is based off of Orson Welles, famous for reading "The War of the Worlds" over the radio on Halloween 1939. Maurice LaMarche, who voiced Simion here, is famous for using his Orson Welles voice when voicing The Brain in the Pinky and the Brain animated series.
Simion: I wanna walk like you, talk like you... ooh-ooh-ooh...
This is from the song, "I Wanna Be Like You," from the 1967 Disney movie, The Jungle Book.
This episode pays homage to Planet of the Apes with its apes-take-over-the-world motif.