I used to really like Family Guy, but I've lost interest in it lately. I suppose what made me dislike Family Guy more than I used to is just how it much it's so politically biased. Not that I really have a problem with that, but what I didn't like is how Family Guy seems to insist that its politics are correct. To me, the show implies (if not blurts it right out) that if you even have a tiny pinch of conservative blood in you, then you are a complete foolish idiot. I am mostly liberal myself, but even so, I find it very annoying how it mocks conservatives so much (considering I used to be a full-blooded one and partially one now). Yes, I know that it's just a cartoon, but I still don't like watching it as much as I used to. Family Guy even influenced me to change a few of my values, which I later "snapped out of" and reverted to some of my original ones. It seems to me that the show is also becoming more and more involved with politics than it used to be.
Actually, one of the things that "bothers" me about Family Guy moreso than its seemingly "stubborn" liberal politics is how it goes too far on some jokes - primarily the 9/11 jokes. If Seth MacFarlane (or any of the other writers) were not bothered or heart broken by 9/11, that's their business, but I think it's atrocious that they make fun of something that is widely believed to be a tragic event. Yes, I know that there is such a thing as dark humor, but I am no fan of dark humor, and so therefore, I do not like how the writers seem to treat 9/11 in such a frivolous manner.
With the exception of that, Family Guy isn't that bad of a show, although lately, I've found that I like South Park a lot better. It seems more jam-packed with adventure and plot development. Family Guy (especially the newer episodes) seems much more stale compared to South Park, or it is in my opinion anyway.