(Frasier has been chastising Martin for his cavalier attitude towards his breakup with Maureen)
Martin: Spare me the Ivy League bull. There ain't a dame alive who wouldn't rather break a guy's heart than think she hadn't even made a dent in it. I may not have been to Harvard, but I have been to the college of love.
Frasier: Apparently, on a Spillane Fellowship.
This references Mickey Spillane, creator of the hard-boiled detective character, Mike Hammer. Hammer's attitude towards "dames", like Martin's, lacked a certain genteel respect.