I absolutely LOVE Frasier. It is very difficult to turn off, so I suggest if you're going to watch it, make sure that you have your whole afternoon free. :) My personal favorite character is Dr. Niles Crane, played by David Hyde Pierce. However, the whole cast of Frasier together make for comedy genius and I hope that there is a Frasier reunion in the works (aside from the slight reunion in The Simpsons Season 19 episode "Funeral For A Fiend" with Kelsey Grammer, David Hyde Pierce and John Mahoney as Sideshow Bob, Sideshow Bob's brother Cecil, and Bob and Cecil's Father, respectively)
On a related note, does anyone know if you can still get Frasier-themed merchandise in Seattle?