There is no comparison to Jonathan Ross in the world, he is outragous (some may say rude) but funny. The questions he asks are very strange and are in some ways similar to questions that Craig Feguson asks on the Late Late Show. The interviews are well structured and include information about upcoming films or albums of his guests and also probes of personal life.
The show is possibly the best mix of interview and fun of any show of its kind. His guests are good and are all put at ease by his style.
Unlike any other show there is a camera in the "green room" where upcoming guests are waiting and interactions with them are good. The audience is allowed to connect with the guests more than just in their interview.
His house band "Four Poofs and a Piano" are great and add to the fantastic mood created by the show.