Grey's Anatomy

Season 4 Episode 1

A Change Is Gonna Come

18
Aired Thursday 8:00 PM Sep 27, 2007 on ABC
9.0
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632 votes

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Episode Summary

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Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. The interns are welcomed by new chief resident Callie. Among the new interns are George, forced to repeat his internship after failing his exams, and Lexie Grey, Meredith's half-sister. Many new interns will be introduced in this season premiere. And they'll have their hands full when a three-car accident sends multiple casualties pouring into Seattle Grace. Some of the doctors need to deal with their new stressed out interns. A young boy brings his bleeding deer to the hospital in the hope a doctor will save her. Cristina searches for Burke. Richard resumes his post as chief of surgery. Derek and Meredith reach an impasse. Bailey wrestles with things at the hospital not turning out like she thought they would.moreless

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Ellen Pompeo

Ellen Pompeo

Dr. Meredith Grey

Sandra Oh

Sandra Oh

Dr. Cristina Yang

Katherine Heigl

Katherine Heigl

Dr. Isobel "Izzie" Stevens

Justin Chambers

Justin Chambers

Dr. Alex Karev

T.R. Knight

T.R. Knight

Dr. George O'Malley

Chandra Wilson

Chandra Wilson

Dr. Miranda Bailey

Mark Pellegrino

Mark Pellegrino

Chris

Guest Star

Sandra Thigpen

Sandra Thigpen

Clara

Guest Star

Stephanie Childers

Stephanie Childers

Nancy Walters

Guest Star

Candice Afia

Candice Afia

Intern Laura

Recurring Role

Amrapali Ambegaokar

Amrapali Ambegaokar

Intern Dani

Recurring Role

Tymberlee Hill

Tymberlee Hill

Intern Claire

Recurring Role

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