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In the 10th-season finale, Cristina's coworkers give her a fond send-off. Meanwhile, a possible terrorist act occurs in Seattle and leads to pandemonium at the hospital; Meredith makes a life-altering choice; and a doctor gets alarming news.
On the day of April's wedding, the Grey Sloan Memorial doctors are all preoccupied with their own drama. Meredith and Cristina continue to argue about their research and careers, Bailey comes clean to Ben about her feelings regarding him moving back to Seattle, and Shane puts himself in a risky situation. Meanwhile, Derek gets a phone call that will change his life.moreless
Arizona's bad day escalates when she advises a patient on a potential double amputation. Derek breaks a promise. Stephanie and Jo find an abandoned baby. The non-fraternization rule leads to a suspension.
When an unexpected malpractice suit turns Callie's world upside down, her supportive father arrives and shares an interesting secret with her. Meanwhile, through flashbacks, we learn some surprising details about Callie and Arizona's marriage.
The doctors face the consequences of the events that took place at April’s wedding. Meredith feels betrayed when Derek goes back on a promise, Alex is furious after returning to the hospital and hearing the news about his father, Arizona and Callie decide whether or not to move forward together, and Bailey realizes she was wrong about the motive behind Ben’s decision to move back to Seattlemoreless
With Derek away, Meredith spends time with Amelia and finds out her true feelings about her time in Seattle. Bailey deals with the ramifications of her actions and Callie receives devastating news. Meanwhile, the residents panic after hearing that one of them will be fired.
The Grey Sloan Memorial Hospital doctors are faced with the devastation left by the storm. A giant mudslide in Seattle injures a group of first responders and citizens, causing the already shorthanded ER to spring into action. Meanwhile, Meredith is faced with a tough decision that will affect the life of a loved one, Callie is rocked by the reality of Arizona's infidelity, and Richard's life is in extreme danger.moreless
Cristina enlists Meredith to help her prepare an acceptance speech for her possible Harper Avery win and while Owen offers to attend the ceremony with her, she insists on going alone. Meanwhile, Derek feels overwhelmed between his responsibilities at home and at the hospital. April and Jackson come to a disagreement on children and religion, and Callie and Arizona try to reconnect in their marriage.moreless
The fight continues to save those affected by the storm, Callie makes a bold decision regarding her relationship, and the doctors come together upon receiving devastating news.
Couples panic when the hospital announces a non-fraternization policy; Owen and Emma discuss the future; Meredith and Cristina have some girl time; Richard asks the residents for help with a rare cancer case.
April’s sisters arrive to help celebrate April’s upcoming nuptials and quickly get on her nerves. Matthew and Jackson are forced to work together when they witness a terrible accident, Callie and Arizona work hard to reestablish their relationship and Cristina is pressured to live stream an upcoming surgery. Meanwhile, a familiar face returns to the hospital.moreless
The doctors are exposed to flu-infected patients. Derek prepares to give a speech. A new doctor gives Alex a glimpse into an alternative medical practice.
The issues between Meredith and Cristina hit a boiling point when one of them ultimately betrays the other at the hospital. Derek tells Jackson that he needs to let go and allow the second year doctors to work on his patients, and April and Matthew make a bold decision about their relationship. Meanwhile, Bailey has difficulties with Ben’s return.moreless
Meredith and Derek adjust to life at home with a newborn but find it difficulty being away from the hospital; Arizona tries to takes steps to fix her broken marriage; Alex and Jo navigate through their new relationship; and Owen clashes with Jackson over financial issues at the hospital. Meanwhile, April anxiously awaits her boards results.moreless
Ben worries that a casual conversation with Derek could potentially cause issues for Bailey, Cristina turns to Shane as tension grows with Meredith, and April’s upcoming wedding makes for an uncomfortable situation between Jackson and Stephanie. Meanwhile, Meredith plans a Thanksgiving dinner at her house.
Bailey asks Richard to join her on the case of a lifetime. Meredith decides to hire a research assistant. Callie shocks Derek. A young pregnant woman needs Shane's help.
The doctors of Grey Sloan Memorial throw a fundraising gala which turns wildly competitive after Jackson makes a rash promise. Back at the hospital, Bailey's patience is tested when she has to deal with several extremely difficult patients. Meanwhile, Shane and Stephanie handle an incredibly busy ER by themselves and Alex reveals an emotional secret to Jo on a very special 200th episode of "Grey's Anatomy."moreless
Meredith jumps back into work but finds it hard to excel at both motherhood and being a surgeon. Stephanie tries to make a good impression on Jackson’s mom, and Jo finds herself overly involved with her new patient. Meanwhile, Callie and Owen deal with an emotional situation regarding a patient.
Derek and Callie work on a brain mapping project, Richard encourages the interns to use his physical condition as a learning tool and after a discussion with Callie, Meredith considers continuing her mother’s research. Meanwhile, Shane continues to feel guilty about Heather’s death.
It's Halloween and the doctors of Grey Sloan Memorial are hit with a barrage of spooky patients, which affects their own plans and puts one doctor’s well-being in jeopardy. Meanwhile, Derek collaborates with Ben on a new surgical technique, and Richard angers Bailey when he asks a second year resident to perform his next surgery.moreless
Cristina thinks about her future. A patient decides whether to live or not.