Grey's Anatomy

Season 4 Episode 4

The Heart of the Matter

Aired Thursday 8:00 PM Oct 18, 2007 on ABC
out of 10
User Rating
438 votes

By Users

Episode Summary

A face familiar to one of the year-twos shows up and dredges up issues that were never really dealt with. A teen football player needs counseling because of his father and surgery for an injury he sustained while playing the game. The girl who was the reason for the prom at Seattle Grace finds out her cancer is back and she brings her aunt Adele with her.moreless

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  • This episode had several story lines involving all the major characters. Callie reacts to George's 'mistake'. Derrick wants more than sex from Meredith.

    Superb acting and great story lines made this my favorite episode of Grey's ever.

    Callie's performance was first rate! She displayed a broad range of emotions (hurt, rage, detachment, disappointment) with her facial expressions and body language as well as delivering her lines in a very believable fashion. The camera close-ups of Richard's face were also excellent. His concern and love for his niece were very apparent with his expressive eyes, voice, and tilt of his head. The interchanges between Christina and Lexie added a great new dimension to the show. Christina is a terrific Nazi - it fits her personality so well. I liked it when Lexie stood up to her saying; "My name is Lexie." after Christina kept calling her '3'. Just when we thought Christina might soften, she calls her '3' again at the end. Nazis never change. I also liked Derrick standing up for Lexie and 'making' Christina be a good teacher instead of just an arrogant condemner. Dr. Bailey is consistently a wonderful actress and it is always a pleasure to watch her work. As usual her performance was dramatic, energetic, and realistic. Of course, the final scene where Derrick lets out his dreams for Meredith and then her typical response was one of the highlights of the show. Their continuing love saga will always be the main part of this show. I've also enjoyed watching the evolution of Alex's character. He finely acts the well-written script for his character. He is finally maturing and not being so selfish.

    Izzie had a good show also - she portrayed a screwed up person really well.

    Adele, George, and the old guy intern are my 3 least favorite characters - they are just plain goofy.moreless
  • A really lousy episode, with excellent but brief parts.

    The beginning of the episode was just dumb. The nothingness followed on, and then Camille's storyline touches you; then Callie unleashes her wrath in an unexpected way...

    About the nothingness, I think the first 30 minutes were an absolute waste of time. Even though the sports guy storyline didn't catch my eye, I think this storyline unearths a very controversial issue: parents pushing their kids too much, over the edge. This happens more than we think, even in CHESS.

    Cristina being rude for no reason, and not being able to respond to her duties, was just as bad as treating Lex as a number. If she's studying under you, then you should be teaching! She's not less because she's an intern.

    Also, hating Lexie has no use or reason. Lexie starts to be under the spotlight, and she is proving that she is a goog person, a good student and a good friend. About this, Mer states that "We hate the idea of her, but we don't hate the actual person"... (And I start to wonder, why do they hate her if she didn't harm her in any way?) That's the second stupidest statement ever said in Grey's Anatomy... Being the other said in 03x22 (A guy says "You can't date Addison, she's a person. or sth like that).

    Cafeteria drama was just lame, and it seems like a tennager's quarrel. I don't know why Izzie thought about fighting since Callie said clearly at the very beginning "We have to talk" This makes all this drama inconsistent.

    I liked what Derek said to Meredith, but I couldn't understand at the time why she would just...ignore him? And Callie is unrescogniscible... She's not the strong, fierce and independent woman whe could see in the first episodes she appeared, now came down to ashes and without a possibility to run away with dignity (what happened to Mer)

    Camille's story was the best part of the episode. Twas' emotional and touching. I think she made a great performance. This and the scenes in which the song "Hawaii" is played are the best moments of the episode. Also, I liked how Alex reacted, truthful and always in his style.

    Then, after the break, it goes down again...

    Mer's narration was just fine.

    All in all, the episode was bad, but near the ending it was very well written, and aimed straight to the heart.moreless
  • Adele brings the chief's niece, Camille to the hospital because her cancer is back. Izzie prepares herself for the showdown with Callie when she finds out George told her about sleeping with Izzie. Derek propositions Meredith.moreless

    So the episode starts out with Callie telling George that she forgives him for sleeping with Izzie. Personally, i already saw that one coming. The next thing that popped into my head though, was will George stay with Callie now and try to work things out, or will he still decide to go back and be with Izzie? George runs all over like a chicken with his head cut off trying to find Izzie. He really starts to panic when he finds out that Callie is looking for her also. Everyone starts making bets and whispering behind doors when Callie confronts Izzie and says she wants to talk to her at lunch. When Callie walks into the cafeteria Izzie prepares to fight Callie street style, but Callie responds by saying she only wanted to talk, so she leaves. Later, Izzie tries to talk to Callie but Callie tells her not to come looking for forgiveness from her. Derek propositions Grey by telling her he wants to take her away for 2 days on a bit of a vacation. Tension rises with Meredith when she realizes that Derek seems to be getting to know Lexie and might even start to be friends with her. Yang tries to step in but Derek keeps coming to Lexie's defense and overriding Yang's decisions. I personally think Derek is stepping out of line and interfering where he shouldn't be. Does he honestly think if he get's close to Lexie that Meredith will want to get back with him or something? The chief's niece Camille gets brought in by Adele and we find out there's a mass in her throat so big that Camille couldn't breathe. We find out the cancer is back and Adele begs Richard to talk their niece into doing everything she can to survive. Richard had to make the hard decision of being her doctor rather than her uncle by respecting her wishes when she told him she didn't want to fight anymore and just wanted to go home. Adele was not very happy with this, and that might be it for him trying to save his marraige. A young football player comes into the hospital with his father/coach and we find out he's paralyzed. His father is so harsh and pushes the boy so hard that the kid breaks down and tells them to make his father leave. The boy needs to have his spine pulled back in place or he might not ever walk again. Lexie made a mistake here by touching his hand while trying to calm him, which could've moved him and screwed everything up. Yang threw her out but Derek stepped in again. A young woman comes into the hospital and reports that she fell off her stairmaster while reading, but her foot is almost completely blue. After finding out that the woman's boyfriend agreed to move in with her only if she got back down to the size he wanted, we realize that she has basically been starving herself. After the woman starts vomiting up a lot of blood we find out she has a very bad bleeding ulcer, which ultimately resulted in her death. Callie freaks out on the boyfriend and Bailey confronts her, telling her she almost lost her career. We also find out that Callie obviously doesn't forgive George. I think part of it is because he really doesn't want to be forgiven yet either. Alex finds out that Izzie slept with George and tells her that he is embarassed for her. I actually think he might be a little bit jealous since he told Izzie that she told him she wasn't ready after Denny's death, and the first guy she sleeps with is George. However, when Izzie is crying at the end of the episode Alex hands her a box of tissues and askes her to keep it down. Could this be a tiny glimpse of compassion? Izzie also brought up Jane Doe in this episode to throw back in Alex's face when she was telling him not to judge her. Derek tells Meredith that this might not be the best weekend to get away, and she gets a little annoyed that he and Lexie have been talking about her. When Grey asks what they talk about Derek told her all the things she was afraid to hear, such as that he wants to marry her, have kids with her, build a house and die old together. He says he'll wait for her, but basically lets her know that it might not be forever. This actually sparked me to wonder even more if we are going to see something happen between Derek and Lexie? Another great episode.moreless
  • My favorite episode besides the last two, of season 4. I felt for Callie in this episode. Mostly because I've been in her situation before.

    I love this episode! It's amazing! I always re-watch it every chance I get. One of my favorites of the entire series. It really gave me a new perception of Callie. The scene that really sticks with me is when Callie and Izzie are talking in the hallway of the hospital, while (Hawaii by Meiko) plays. I love that song! I also liked the stuff with the Chief's niece...sad. I've been in Callie's shows's very awkward, especially when you really love the person who cheated on you with someone you know, a friend, and you act like you've forgiven them, but you can barely look at the person. And you want to pretty much kill the person they cheated on you with. It's so messy! So I definitely felt for Callie in this episode. Very good!moreless
  • Loved it. My favourite of the season so far!

    I loved every minute of this episode, it was funny, emotional and the medical cases were good to. There was not one character I didn't enjoy this episode. The whole fight at noon thing was so funny, Izzie putting up her fists, taking of her shoes and earrings was all just hilarious. But then Callie came and thought Izzie just stop before ... but then it was too late. I think it was fair what Callie said to Izzie, though I am routing for Gizzie. Alex I guess had a right to be angry she did turn him down, the tissue thing at the end was nice. The start with George running was again just so funny. Cristina and Lexi, what a pair. I liked the way Cristina had the power but it kept being taken away by Dereck. I'm glad she said sorry in her own way. Derecks speech was great and about time he said it as well. I liked Merediths reaction as well, it hinted that they could back together but on the other that they might not. Like her relationship with Norman in this episode. So as you can tell I loved this episode and hope the rest of the season will be as good (I have a feeling it will be). Next weeks sounds brilliant!moreless
Ellen Pompeo

Ellen Pompeo

Dr. Meredith Grey

Sandra Oh

Sandra Oh

Dr. Cristina Yang

Katherine Heigl

Katherine Heigl

Dr. Isobel "Izzie" Stevens

Justin Chambers

Justin Chambers

Dr. Alex Karev

T.R. Knight

T.R. Knight

Dr. George O'Malley

Chandra Wilson

Chandra Wilson

Dr. Miranda Bailey

Edward Herrmann

Edward Herrmann

Dr. Norman Shales

Guest Star

Michael McGrady

Michael McGrady

Stanley Singer

Guest Star

Matt Lanter

Matt Lanter

Adam Singer

Guest Star

Loretta Devine

Loretta Devine

Adele Webber

Recurring Role

Mark Saul

Mark Saul

Intern Steve

Recurring Role

Gloria Garayua

Gloria Garayua

Intern Graziella

Recurring Role

Trivia, Notes, Quotes and Allusions


  • TRIVIA (0)

  • QUOTES (34)

    • Lexie: I just wanted to say thank you for saving my ass in surgery today.
      Cristina: That's my job, 3.

    • Adele: I already lost one baby, now I have to lose Camille, too.
      Richard: I am not going to use to Camille to try and make up for the fact that I never gave you children.
      Adele: I didn't ask you to. I asked you to talk to her, to convince her--
      Richard: I can't do that. ... I can't do that Adele. I can give her all the options in the world, but I cannot make her do what I want her to do. I'm her doctor.
      Adele: I thought being a doctor was about saving lives. After all these years, of choosing your job over your family... The one time that I ask you to do your job to save this family.
      Richard: Adele, I'm sorry. I'm truly, truly sorry.
      Adele: So, am I, Richard. (walks away)

    • Mark: I'm writing you both up.
      Meredith: It wasn't Norman's fault, He's my responsibility, I'm the resident, I'm the only one that you should write up.
      Mark: That's very noble of you, Dr. Grey. Stupid, but noble. (walks away)
      Norman: For the record, Dr. Grey, I don't find you stupid at all. I find you quite smart. (Meredith smiles)

    • Izzie: What? Am I invisible now?
      Alex: What do you want?
      Izzie: Oh, so you hate me now too? Join the club.
      Alex: You and O'Malley. O'Malley!
      Izzie: What? What is it that I did that is so horrifying? (pauses) I fell in love, Alex.
      Alex: He's married.
      Izzie: Yeah, so? You're carrying a big ol' torch for Ava. Or Jane Doe. Or whatever it is that you call her and she's married. What gives you the right to judge what I do? Why do you even care?
      Alex: You told me that you weren't ready yet, after Denny, to be with anyone. And then O'Malley... O'Malley! ... And then you tell me like I'm one of your chick friends, come on! (walks away)

    • Izzie: I'm just saying, I learned how to fight in a trailer park. Where'd she learn how to fight? A boarding school? Not quite the same thing. (Callie enters the cafeteria, Izzie is unaware, Callie walks towards her. Everyone is staring) I'm a street fighter, I got some bad ass in me. I can take a girl down.
      Callie: Izzie.
      Alex: Punch with your left, protect your face with your right.
      Cristina (eating popcorn): No, protect your hands. Your surgeon hands. Your face can heal.
      Callie (clears her throat): Stevens.
      Izzie (putting her hair up, and taking out her earrings): Let's do this. Let's go. Let's go. (cracks her neck)
      Callie: Go... where?
      Izzie (puts her fists up): You know... Go.
      Callie: I wanted to talk.
      Izzie: You wanted to talk? (puts her arms down) You didn't wanna kick my ass?
      Callie: You thought I was gonna fight you? (scoffs, then realizes everyone is watching and walks out of the cafeteria)
      Intern: That's a forfeit, Torres forfeits!
      Izzie (sits back down at the table): Oh my god.
      Cristina: You were very ghettofabulous.
      Izzie: Oh, my god.
      George (runs in): What happened, was there a fight?
      Alex: No. I guess they realized that they were fighting over nothing.

    • Winnie: So, who's your money on O'Malley? I guess you gotta back the wife, huh?
      George: What? What're you talkin' about?
      Winnie: The fight downstairs. Torres vs Stevens. What're they fightin' about anyway?
      George: Oh, Winnie, that's just a rumor. It's not happening. Callie's too mature for that.
      Winnie: That's not what my buddy in the cafeteria says. (George runs away towards the cafeteria)

    • Cristina: I'm not a bad resident, am I?
      Meredith: Don't ask me. I lost a patient today.
      Cristina: Oh, you killed someone?
      Meredith: Lost. Literally can't find.
      Cristina: Oh. Shepherd says I'm selfish and competitive. What the hell is wrong with that? I kick ass. I'm an excellent resident.
      Meredith: I'm not. In addition to losing my patient, I also lost my intern. Turned around and he was gone. AWOL.
      Cristina: See? What is wrong with these interns? We weren't like this.
      Meredith: We were great interns.
      Cristina: I was great. You were... you were good. (Meredith gives her a look)
      Izzie (sits down, a bit panicked): You guys seen Callie?
      Cristina: No. Oh, is it time for her to grind your bones into dust?
      Izzie: Oh, you don't think I can take her?
      Meredith: Are you guys really doing this?
      Izzie: You heard?
      Meredith: The whole hospital heard.
      Izzie: Well, that explains the line at the salad bar.
      Meredith: What are you fighting about?
      Alex (sits down): Believe me, you don't wanna know.
      Izzie: Alex.
      Alex: I'm just saying whatever it is, it's not worth it.
      Izzie: Actually, it is. Somethings are worth fighting for.

    • Derek: You are a resident now, your job is to teach interns, not be--
      Cristina: I wasn't. She --
      Derek: Until, you learn to be less competitive and less selfish you will not assist on my surgeries. You will only observe them.
      Cristina: But she--
      Derek: You can go now.

    • Meredith: I just had to tell a 48 year old woman that's she's gonna die.
      Cristina (referring to Lexie who's laughing with Derek): I wish I could tell a 24 year old woman that she's gonna die.
      Meredith: I have gone out of my way to be nice to her and this is what she does, talks about me behind my back.
      Cristina: When were you nice to her?
      Meredith: I was nice... once. My point is...
      Lexie (walks up): Hey, Meredith, hey Norman.
      Norman: 'Sup, Lexie?
      Meredith: Come on, Norman. (they walk away)
      Lexie: Um... Dr. Shepherd asked that we meet in Adam's room in ten minutes. (Cristina ia silent) You can at least aknowledge that you heard me.
      Cristina: You're using the Grey- Sister Triangle to get in good with the attendings. I got that. But you're on my license, so if you do anything, like kill someone, it's on me. So, for the rest of the day, you're gonna hug the wall, you're not gonna say anything, you're not gonna do anything, are we clear... 3?
      Lexie: It's Lexie.
      Cristina: What?
      Lexie: It's Lexie or Grey. It's not three. I have a name.

    • Izzie: Well, what're you doing at lunch?
      Alex: Well, according to my interns, I'm gonna be watching Torres kick your ass up and down the cafeteria.
      Izzie: How do they know?
      Alex: So it's true. What'd you do to her?
      Izzie: Nothing.

    • Cristina: Hey, are you aware that McDreamy and the other Grey are bonding?
      Meredith: Bonding?
      Cristina: Over their mutal Meredith Grey-ness.
      Meredith: What do you mean? They're talking about me? What are they saying?
      Cristina: Oh, I don't know. He's making me deal with his patients, while they focus on what's really important. You.

    • Meredith: So, when giving the patient the bad news, you want to be polite and detatched but not cold.
      Norman: How can you be detatched but not cold?
      Meredith: You show that you care without actually allowing youself to care, because if you get too emtional, then they get scared. And then they get emotional. And that's bad.
      Norman: Seriously?
      Meredith: Stop with the seriously.

    • Meredith: Dr. Sloan, Dr. Norman Shales.
      Mark: Ah, nice to meet you Dr. Shales. You can call me Mark. (to Meredith) I thought you were on my service?
      Meredith: I am. He's my intern.
      Norman: I know, it's like seriously you're an intern? But it's seriously true. Seriously.
      Mark (hands him charts): Glad to have you aboard, Norman. (walks away)
      Norman: So is he the one you call McDreamy, or McSleezy, or Mc... Wait, what was the other one?
      Meredith: We have labs to deliever, labs and discharges.
      Norman: Uh, this one's being discharged to HOSPIS?
      Meredith; Well, there's nothing else that we can do.
      Norman: So we have to tell someone their dying?
      Meredith: Don't worry, I'll teach you the protocol.
      Norman: McSteamy! He's the one you girls call McSteamy!

    • Derek: So, how's it going, you and Meredith?
      Lexie: It's weird, the whole family thing. And plus, I think she still might hate me. (Cristina rolls her eyes)
      Derek: She doesn't hate you.
      Lexie: Really? Did she say--
      Cristina: You know, why don't you go see if Mrs. Colie's dressing needs changing.
      Derek (to Cristina): Yeah, why don't you go see if Mrs. Colie's dressing needs changing.

    • Cristina: Focus more on the medicine, 3, and less on the tragedy.
      Derek: 3, is that a nickname?
      Lexie: You could say that. (Cristina glares at her)

    • George: I'm sorry, I just gotta find Izzie.
      Richard: She's at the third floor nurses' station.
      George: Thanks.
      Richard: Oh, and when you find her can you tell her Dr. Torres is lookin' for her.

    • George: Have you seen Dr. Stevens?
      Lexie: No, have you seen Dr. Yang? She told me to meet her in the pit and she's not here. I don't wanna give that woman any more reasons to hate me.
      George (distracted): Good for you.
      Lexie: I'm prepared, I'm gonna answer every question correctly, I'm not gonna take any more of her crap.
      Cristina: 3! Incoming, let's move!

    • Meredith: Will you work for me on Saturday?
      Alex: What's in it for me?
      Meredith: What do you want?
      Alex: Take Norman off my hands today.
      Meredith: Who?
      Alex: The world's oldest intern. I got my interns in the pit today and he's only gonna slow me down.
      Meredith: Age-ist.
      Alex: Deal?
      Meredith: Fine.

    • George: Callie. You can't just forgive me. What I did to you, it's unforgivable.
      Callie (without turning to face him): That's how it works. That's what I forgive you means.
      George: No, see, I think it means you don't forgive me. And you don't know how to talk to me right now, and I mean... Look! You don't... you can't even look at me. You're so angry that I think the only way you can deal with me is to say you forgive me and what... we pretend it didn't happen? It happened, and you don't forgive me.
      Callie: You're right, I don't.

    • Izzie: Callie... (Callie stops walking, but doesn't turn around) Callie wait, please, wait. I'm sorry about the cafeteria. I didn't think you wanted to talk to me. I thought you wanted to kill me. (Callie now turns to face her) I'm sorry about everything... with George, I... I'm really sorry. I feel terrible.
      Callie (walks past Izzie, but stops and turns around): You feel terrible? You took advantage, he was your best friend. I tried to trust you. So much that I convinced myself that it was all in my head, that I was crazy. But I wasn't, was I? And then you pulled that thing in the cafeteria today. It's not bad enough that you humiliate me by getting in bed with my husband, you have to humiliate me at work too. George may be the one who broke his vows but you... we're women, Izzie. You did this to another woman. You took something from me. You stole something from me like a petty little thief. You are the one who should be humiliated. You are the one who should be ashamed. You are the one... don't you dare come to me for forgiveness you traitorous bitch.

    • Callie: I thought you quit smoking. Wasn't that the deal? Ruthie loses 40 pounds and you quit smoking?
      Will: My girlfriend's in emergency surgery, I think she'll forgive me for smoking.
      Callie: No, no she won't, because she's dead. Ruthie's dead. Dr. Bailey tried to stop the bleeding but because shes been starving herself and over training, her heart couldn't take the strain!
      Will: You think this is my fault? She wanted to lose the weight. I just wanted her to be healthy.
      Callie: She was healthy 20 pounds ago. You just wanted her to be hot, especially if you were gonna move in with her right?
      Will: Look... I loved her.
      Callie: You didn't love her! You just didn't want to be alone. Or maybe, maybe she was good for your ego. Or, or maybe she made you feel better about your miserable life, but you didn't love her, because you don't destroy the person that you love!
      Will: Get her away from me!
      Callie: You gonna hit me? You gonna hit me?! Give me some excuse to kick somebody's ass!
      Bailey: Dr. Torres! Sir, we are so sorry for your loss. O'Malley why don't you take...
      George: Sir, why don't you come with me? Come on. (they walk away)
      Bailey: Okay I'm gonna ask you one last time. Are you alright?
      Callie: I'm fine. It's nothing.
      Bailey: Really? Because nothing almost cost you your career just now.

    • Derek: Hey, what do you think is a better weekend getaway? Napa or Sonoma?
      Mark: I hope you don't mind if I kill your girlfriend.
      Derek: Well, first of all, she's not my girlfriend. And second of all, I do mind.
      Mark: Interns should be seen and not heard. They shouldn't talk to patients.
      Derek: Well, that's how they learn.
      Mark: Which means that I have to teach and deal with their problems when they screw up.
      Derek: Meredith rarely screws up. She's not an intern. So, Napa, Sonoma, what do you think?
      Mark: Sonoma. Smaller hotels. Fewer tourists. And Meredith, she's still an intern don't kid yourself. She's green, she's a baby, and the only difference between her and the old guy she's got trailing her is that you're not sleeping with the old guy.

    • Alex: So, what's it gonna be? Stevens gets her bones broken? Or Callie gets taken to the trailer park?
      Izzie: Neither. It's not happening... but, if it does, will you pull her off of me?
      Alex: You gonna tell me what you did to her?
      Izzie: You have to promise not to say anything to anybody. Swear.
      Alex: I swear. Geez.
      Izzie: I slept with George. I know, I know, I'm a terrible person, which is why I'm gonna let her get one punch in... or two because I deserve it ... No, one and then you pull her off me.
      Alex: You slept with O'Malley.
      Izzie: Alex, you said you weren't gonna say anything.
      Alex: I won't, believe me. I'm embarrassed for you.

    • Izzie: She forgave you?
      George: She said that I had a rough year, and that people make mistakes. And ... that I made a mistake.
      Izzie: Oh, so now I'm a mistake? (George clears his throat and motions to her interns) Back off!
      George: No, she said that. I didn't say that.
      Izzie: What did you say?
      George: Um... I didn't expect her to forgive me. I excepted rage, um... bloodshed.
      Izzie: No, she's saving all her rage and bloodshed for me. And she's gonna kill me in the cafeteria at lunch.
      George: No, she wouldn't.
      Izzie: She breaks bones for a living George, she's crazy!
      George: No, she's not crazy.
      Izzie: Well, she is if she thinks I'm not gonna put up a fight.

    • Cristina: Oh... great... I'm stuck in the pit taking smack heads and gang bangers with my idiot interns and you're getting McDreamy'd in the elevator.
      Meredith: Really, smack heads and gang bangers at Seattle Grace, huh?
      Cristina: My point is, I hate interns.
      Meredith: Well, Lexie's not that bad is she?
      Cristina: Oh, are we not hating her anymore?
      Meredith: Oh no, we still hate the idea of her. We just realize we don't have reason to hate the actual person.
      Cristina: She's an intern. That's reason enough.
      Meredith: Oh, I think you may be the new Nazi.
      Cristina: Damn right.

    • Derek: You wanna go away with me this weekend?
      Meredth: Why would I wanna go away with you?
      Derek: Because of this. (kisses her hard)
      Meredith: We didn't go away when we were a couple and now we're not a couple. Not-couples have no reason to go away together.
      Derek: Meredith, you're not paying attention. I'm talking about 48 uninterrupted hours of this. (kisses her again)
      Meredith: Well, where are we gonna go?
      Derek: Wine country.
      Meredith: Wine country sounds like a couple's place.
      Derek: Well, there's wine, there's country, but we wouldn't see any of it. (kisses her again) We'd be in bed all weekend.
      Meredith: Ah, a weekend of sex.
      Derek (smiles): See, now you're payin' attention.
      Meredith (smiles): Well, I would have to get someone to cover for me.
      Derek: Okay, so you're in?
      Meredith: 48 uninterrupted hours of this. I'm in.

    • George: Callie... you haven't said anything and... just say something... please, anything.
      Callie: I forgive you.
      George: What?
      Callie: You made a mistake, but we took vows, 'til death do we part so...I forgive you.

    • Richard: Camille, what took you so long to come here?
      Camille: I knew the cancer wasn't gone. It was never gone, it's never gonna be gone. And... don't tell my mom, but the truth is... I was hoping that it would kill me before I ever had to come back here. I'm just so tired, Uncle Richard. I am so, so tired.
      Richard: What I have here is a plan to keep you alive. It involves, 12 oncologists, 8 new drugs, 6 experimental procedures, from 3 different continents. I have no idea if it'll work, but as your Uncle, I'm begging you to take it. Because I know for a fact that the world... my world is a better place with you in it. However, as your doctor, I promise to do whatever you want.
      Camille: I just wanna go home.
      Richard: Then let's get you home.

    • Meredith: Hey, I got Alex to cover for me. So, I just have to round on my patients and then I can leave. 48 uninterrupted hours.
      Derek: Yeah. Yeah. Um... maybe this isn't a good idea.
      Meredith: What'd Lexie say about me?
      Derek: She didn't say anything. I did all the talking. Oh, don't blame her.
      Meredith: So, what? You're friends with my sister now? I mean, you talk to the other Grey, about me.
      Derek: You know what I talked about with the other Grey? All the things this Grey won't let me say.
      Meredith: You can say anything to me.
      Derek (pause): I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old in your arms. I don't want 48 uninterrupted hours. I want a lifetime. (Meredith steps back intimidated)
      Meredith: Mm-hmm...
      Derek: Do you see what happens? I say things like that, and you fight the urge to run in the opposite direction. It's okay. I understand. I didn't, but now I do. I do... You're just getting started, and I've been doing this for a long time. Deep down, you're still an intern. And you're not ready.
      Meredith: I'm not ready right now. But things could stay the way they are, and I can get ready. I'll get ready.
      Derek: Things can stay the way they are. We can still meet in the elevator or the on call room. And maybe you'll be ready. And I'll wait. I'll wait until you're ready.
      Meredith: Okay, then.
      Derek: Yeah, but what if...What if while I'm waiting I meet someone who is ready to give me what I want from you?
      Meredith: What if you do?
      Derek: I don't know.

    • Izzie: Callie!
      Callie: Hey.
      Izzie: Hi.
      Callie: We have to talk.
      Izzie: Okay. Hmm, about?
      Callie: George told me.
      Izzie: He told you?
      Callie: Everything. Cafeteria, noon, you and me. Be there. (walks away)
      Intern (to other intern): Dude, is she gonna kick her ass?

    • George: Why did she do this to herself?
      Bailey: People are stupid and just want to be loved. That's the only reason anyone does anything.

    • Izzie (to her interns): Now I know charting doesn't seem as exciting as surgery, but it is as important. Believe me when I tell you, penmanship saves lives! Is that a 7, or is that a 9? If I have to ask myself that in the middle of an emergency, your patient is dead. You killed him. With your handwriting. Think about that!

    • Meredith (closing voiceover): Forgive and forget. That's what they say. It's good advice, but it's not very practical. When someone hurts us, we want to hurt them back. When someone wrongs us, we want to be right. Without forgiveness, old scores are never settled… old wounds never heal. And the most we can hope for, is that one day we'll be lucky enough to forget.

    • Meredith (opening voiceover): In life, only one thing is certain, apart from death and taxes. No matter how hard you try, no matter how good your intentions, you are going to make mistakes. You're going to hurt people. You're going to get hurt. And if you ever want to recover… there's really only one thing you can say.

  • NOTES (4)

    • International Episode Titles:
      Czech Republic: Jádro pudla (The Heart of the Matter)
      Slovakia: Jadro veci (The Core of the Matter)

    • Original International Air Dates:
      Italy: Monday, January 7, 2008 on Foxlife
      Saudi Arabia: Tuesday, January 22, 2008 on ShowSeries
      Australia: Sunday, February 18, 2008 on Network 9
      Latin America: Monday, March 3, 2008 on Sony Entertainment Television
      Germany: Wednesday, March 5, 2008 on ProSieben
      Finland: Wednesday, March 19, 2008 on Nelonen
      The Netherlands: Monday, March 31, 2008 on Net 5
      Croatia: Thursday, April 3, 2008 on RTL TV
      Israel: Monday, April 7, 2008 on YES Stars 1
      Czech Republic: June 1, 2008 on Prima
      Norway: Tuesday, September 16, 2008 on TV2
      Romania: Tuesday, October 28, 2008 on TVR1

    • Music Featured In This Episode:
      1. Sun Comes Up by John Legend
      2. Hawaii by Meiko
      3. Better Already by Northern State
      4. Milk and Honey by Prince Fatty feat. Hollie Cook
      5. The Absence of Your Company by Kim Richey
      6. Rockers to Swallow by Yeah Yeah Yeahs

    • The character Camille, in this episode played by Camille Winbush, was originally presented in season 2 and played by Tessa Thompsson.


    • Episode Title: The Heart of the Matter

      The title of this episode is a reference song by Don Henley, released in 1989. The Heart of the Matter is also a famous song by soul singer India Arie.