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Goof: Dr. Virginia Dixon tells Bailey that the first successful heart transplant was performed in 1896 by Dr. Ludwig Rehn, which is a very serious mistake - in 1896 Dr. Ludwig Rehn actually performed a very first successful heart surgery in recorded history, but not a heart transplant. First cardiac transplantation was performed only in 1967 by Dr. Christiaan Barnard in South Africa. It's hard to believe that Dr. Dixon would make such a mistake in her area of expertise.
Goof: In the first parts of the episode, Izzie is wearing a long-sleeved red shirt beneath her hospital clothes, but, in the end, when she is about to change, you can see that she doesn't have it anymore.
Jeffrey Dean Morgan (Denny Duquette) although appearing throughout the entire episode, only says the last five words "Are you sure you're okay?"
At approximately 31mins, Sloan and Torres are in bed together. When Shepherd comes in, Torres completely hides her head and arms under the cover. After some brief talking, Shepherd leaves, and now only her head is covered and her arms are completely visible.
When Meredith starts reading her mother's diary the date on the first page is Oct. 13, 1977.
Goof: When George is showing Dustin the video camera in the OR, he twists it back and forth, so that the picture on the monitor moves too. When the shot cuts away from the OR monitor, the image of Dustin is at an angle. In the next shot, the image is at a completely different angle, even though George let go of the camera.
At the end of the episode you can see a "Dermatology" sign on the door of trailer. It looks like an actual Derm sign that one of them stole perhaps, as opposed to a simple sign with the word "Dermatology" written on it.
Cristina's phone is a red Blackberry pearl, 8130 series.
Throughout the episode Dr. Walter Tapley repeatedly refers to George as O'Leary.
The Chief's phone is a Blackberry Curve 8000 series.
Derek's middle name is Christopher.
When inquiring about Callie's relationship with Hahn (specifically, whether or not they're a couple), Addison asks, "Are you performing in the Vagina Monologues now?" Actress Sara Ramirez, who portrays Callie, acted in The Vagina Monologues along with Tovah Feldshuh and Suzanne Bertish.
Alex is seen working at the hospital. However, he was suspended for one week in the last episode for having Ava in the gallery which was only a day of difference.
Goof: Rose mentions that she took three semesters of computer science at Santa Cruz. However, UC Santa Cruz operates on a quarter system, not a semester system.
Goof: Marks says he went to New York to study under a pre-eminent surgeon after he left Columbia Columbia University is in New York City
Goof: Stan's nameplate before the accident was "S. Hayden." After the accident, it changed to "S. Glamatti."
The sign on the notice board announcing that Callie is Chief Resident lists the names of "Arriving interns/General surgery" underneath. These names are all of members of the show's crew.
We get to know that Bailey and Derek played in the marching band in high school. Miranda played the oboe and Derek played the saxophone.
Lexie is 24 years old.
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dramedy, fighting doctors, relationship woes, for women, unrequited love