Goof: When Callie and Addison are talking about having a baby, Addison puts her hands on the front of her face, in the next scene, they are on the top of her head.
When Addison is apologizing in the elevator for yelling at the elevator voice, the song playing is "Your Song" by Kate Walsh. Kate Walsh is also the name of the actress who plays Addison, but they are not the same person.
When Jane Doe/Ava speaks German she says: "Alex, ich brauche die nächste Karte. Das ist noch das Haus." ["Alex, I need the next card. This is still the house."]
Goof: When George gets on the elevator, Izzie is waiting to get off at the 4th floor and George presses the button for the 5th floor; however, when the door opens (on the 4th floor) he gets off and she stays on.
This episode is the first part of the "enhanced Grey's Anatomy episode with a potential for afterlife", meaning the backdoor pilot to what could become the Grey's spinoff if picked up by ABC called "Private Practice". It was picked up.
Goof: When Addison is inspecting the wedding cakes, we hear her say, "White chocolate with vanilla buttercream..." but her mouth does not move at all.
Goof: In the credits "Danny Scott Lux" is listed as having done the music twice.
Alex's favorite pie is Banana cream.
Goof: When George is having lunch with Callie and her father and he remembers having sex with Izzie, he is wearing civilian clothing. But when he walks up to Izzie in the hospital right after, he is scrubs. It's unlikely that in the middle of an emotional crisis he took the time to change.
When Cristina and Preston were lying on the bed, Preston was reading Dreaming of Bird.
Goof: Alex said before that Jane Doe had very distinctive brown eyes, but in the scene where Alex helps her choose her new face, her eyes look blue.
Jeff Perry and James Gammon both appear as guest stars in this episodes, they previously worked together on the 90's cop series Nash Bridges.
When Izzie walked in we didn't see bring the bottle of lotion she was using while talking to Meredith and when she walked out she didn't carry it either.
Goof: When Izzie trips the breaker in the kitchen, the entire house wouldn't lose power as they imply it to be. Only the kitchen would have lost power until the breaker was fixed.
Goof: In the scene the interns are having lunch there's a shot showing Cristina's sandwich having two bites followed by a shot in which it has only one.
In the scene where Meredith's heart starts beating on its own again, we can see a poster of a doctor on the wall next to the door. But, in the following scene, when Addison enters the room, the poster is gone.
Goof: When Derek visits Meredith in her hospital room, she is hooked to two parallel wires, one red and one white. In one shot, the white wire is on the left but, in the next, it is crossed over the red one. In the very last shot of the scene, both wires are gone.
Goof: During Meredith's resuscitation, an endotracheal tube is shown extending what appears to be six to eight inches past her lips. This would be incorrect placement in an adult; the end of the tube should be only one to two inches past her lips.
Goof: During the scene where Meredith is mostly-dead she encounters several important people from her past, and previous episodes. She is seen with Denny and Dylan, and her dog Doc, as well as Bonnie who dies in episode 206 after a tragic train wreck. Meridith also meets up with Liz Fallon again, the woman who was her mother's scrub nurse for 18 years and the first confidante to know that Ellis Grey had Alzheimer's. When Liz asks Meredith if she remembers her Meredith says yes, and that Liz died of Liver Cancer. This is inconsistent with the information from episode 104- No Man's Land- when Dr. Yang steals Nurse Fallon's chart to try and get in on a good surgery. In that episode Liz dies of Pancreatic Cancer, not Liver Cancer.
Goof: Right after the shot from Ellis Grey to Meredith Grey, you can clearly see an artery moving by Meredith (around 25.00 minutes).