The episode is focused on April and Jackson's history throughout the episodes since they first met, but we see it in a backwards timeline.
From the moment April is about to sign the divorce papers, we go backwards to the momet they met, and vice versa after that.moreless
Against Alex's advice, Callie and Maggie perform a risky surgery on a teen and everyone deals with Meredith’s trauma.
A patient attacks Meredith and Penny finds her wounded, so Meredith's coworkers race to save her and wait by her side as she fights to survive.
Injured firefighters arrive at the hospital after battling a wildfire. Meanwhile, Maggie has trouble maintaining just a professional relationship with Andrew at work; and Jo wants to know what Alex's priorities are.
A high-stakes case is tackled by a team of doctors, and the atmosphere grows tense. Meanwhile, Bailey pressures Ben to evict their roommate; and Arizona enthusiastically reenters the dating scene with a new wingman.moreless
A transfer resident arrives at the hospital. Meanwhile, Richard wants his relationship with Maggie to evolve; gossip follows a patient who mistakenly sent his sex tape to his congregation; and April presents a case involving a boy from the Middle East.moreless
Maggie leaves her dinner party and races to the hospital, so April takes over the cooking duties in an attempt to dodge Jackson. Meanwhile, Arizona is anxious about meeting Callie's new girlfriend.
Owen teaches an important lesson to the interns regarding breaking bad news to patients' loved ones. Meanwhile, Arizona's elderly patient tells her not to give up on finding love; and a dinner party gets off to a bad start when the hosts forget about it.moreless
Maggie reflects on her life when her old beau gets married. Meanwhile, Bailey's allegiance is questioned by Richard; Jo tells Stephanie a secret she's been hiding from Alex; and Alex faces a tough decision regarding newborn twins.moreless
Bailey begins her first day as chief of staff and feels the pressure that accompanies the position. Meanwhile, April finds her marriage is in peril; Meredith has trouble balancing her many obligations; and Amelia tries to define what she has with Owen.moreless
Meredith adapts to new roommates. Meanwhile, Jackson gets ready for April's return; Bailey battles to be chief of surgery; and two young patients propel the doctors to reexamine bullying scenarios from their own pasts.moreless
In the 11th-season finale, the doctors are busy dealing with the aftermath of a disaster, which bonds them as it reminds them about what to prioritize in life.
Richard calls off the wedding. Amelia fights with Meredith about letting Derek die and Maggie gets some bad news.
The impact of Derek's death is felt by Meredith and her coworkers. Meanwhile, April makes a surprising decision, which leaves Jackson baffled; and Bailey and Ben disagree about their future.
Derek sees a ghastly accident and jumps into action to help the wounded.
A small plane crash occurs, triggering bad memories for Meredith and Arizona as injured victims are brought to the hospital. Meanwhile, tension between Owen and Amelia creates an awkward work environment for Stephanie.moreless
Upon realizing that Owen and Amelia have been seeing each other behind her back, Meredith comes down hard on her sister-in-law causing Amelia to rethink things. Meanwhile, Catherine springs into action when a man is brought into the hospital after his wife seeks revenge on his cheating ways.moreless
A group of children visit the hospital on a field trip and observe two injured cops rushed into the emergency room. Meanwhile, Stephanie develops a crush on one of the chaperones; and Amelia's forced confront her feelings about Owen.moreless
Rattled by recent events, Meredith tries to decide what to do about Derek; Owen is stunned when his mother is admitted to the hospital.
A man with Alzheimer's crashes into a pregnant woman; Meredith worries about Derek cheating on her and the date of their marriage.
An earthquake leaves Maggie trapped in an elevator and threatens Meredith's streak of successful surgeries; Owen gives medical advice over the phone.
The moment of truth has arrived. Amelia begins the daunting surgery to remove Dr. Herman's tumor. Meanwhile, Arizona takes the lead on a case that means a lot to Dr. Bailey.
The hospital doctors become fascinated with Dr. Herman's case when Amelia gives a lecture detailing the intricacies of the surgery. Arizona and Herman continue to bond over the amount of cases they are trying to complete before the big surgery. Meanwhile, Bailey brings them a case of a pregnant woman who is close to her heart.moreless
Maggie gets upset when Meredith dodges her questions about DC; Bailey and Ben become concerned about Ben's brother after he is admitted to the hospital, and Dr. Herman starts to warm up to Arizona. Meanwhile, Richard feels manipulated by Catherine.moreless
April and Jackson face a tough decision concerning their unborn baby. Elsewhere, Catherine encounters Richard at the hospital; Meredith searches for a babysitter so she can visit Derek; and Amelia tries a tough-love approach while working with Stephanie.moreless
April stays positive as tests are run on her baby; Dr. Herman plans a crash course in fetal surgery; Callie and Owen encourage each other to return to the dating scene; Bailey, Meredith and Maggie try to learn more about a patient's tumor.moreless
Meredith keeps herself busy while Derek prepares for his move; Jackson and April get difficult news; Arizona and Amelia talk about how best to approach Dr. Herman.