Grey's Anatomy

Season 3 Episode 14

Wishin' and Hopin'

Aired Thursday 8:00 PM Feb 01, 2007 on ABC
out of 10
User Rating
644 votes

By Users

Episode Summary

The chief's announcement of his retirement sparks competition between Derek, Burke, Addison, and Mark. A surgical patient endangers the lives of those surrounding her. Meredith's mother becomes lucid. Cristina and Callie consider marriage proposals. The Denny Duquette Memorial Clinic opens and Izzie cannot wait for the first patient to arrive.moreless

Who was the Episode MVP ?

  • Again, an excelent epi with both action and revealing stories. Ellis being lucid again: flawless.

    It was an excelent episode. I liked how Ellis became lucid (totally uncalled for but excelent anyway) and didn't save anything for herself and spoke out loud what she thought throughout this episode. She is the strongest woman of the show, let me say.

    Seeing Izzie and the clinic was really funny. The marriage between Callie and George, I didn't like it at all, but it was funny to see the rest of the gang lashing out at her. The drama of the lady with toxic blood was original, and I really liked how everyone risked their lives to save the rest. I liked the chief, Meredith, and seeing the Addison hormonal situation about Alex! Funny! Just funny! The thing is, I didn't like when she slept with Mark, when she's thinking about Alex. Only this time I have to say no to the idea of them being togheter.

    Ellis lucid final scenes were great, with the chief, and the scene when she says "You remind me of my daughter"...that was the best, really well written, but I saw it coming from miles away, it was obvious it was going to be a revolution of only one episode.

    Excelent episode! It will always be remembered by all the tv watchers!moreless
  • This episode is a series classic, the best of season 3 and if I had to choose one episode of Grey's I liked best, this would win hands down!

    This episode is brilliant. Meredith's mother is lucid and she's very nasty. I liked how Meredith told her off and blamed her for everything, because in my opinion, she needs someone to tell her that she can't continue to treat people like they don't matter. I love the fact that all of a sudden, I could actually sympathise with Meredith and in this episode, I really didn't find myself wanting to slap her as much as usual. Izzie's one of my favourite characters, but I hated the fact that she turned her back on helping a patient with a legitimate question. Obviously the clinic will take time to get on it's feet, but she expected results. In my opinion, the clinic was an excellent idea of Dr Bailey's and I'm glad she took the time to help the patient, which I respected. George and Callie are prehaps my least favourite couple on TV. They're just not suited to each other. I mean, George just lost his father and it seems like Callie's taking advantage of that. But even though I hated them getting married and them as a couple, I like George and I like Callie. I love Alex's reaction "Dude, she's Callie O'Malley!" That was brillant. But the main reason I watch this episode is because of the toxic blood storyline. I did not see that coming myself. When George was acting weird, I thought it was because of Callie and when Olivia said she was sick, I thought she was faking it because of her earlier conversation with George. I think Addison was heroic in that episode by putting the patient back under the ansethesia. I do think that they set up the end to make the girls look like the heroes by going in, but in my opinion the hard work was already done. This episode to me is one of the best in the entire series and I don't think that that will ever change for me. It's brillant, superbly acted and it's just got a great storyline that kept me hooked the entire time!moreless
  • Meredith's mother winds up at Seattle Grace lucid, and with her memory back. George and Callie announce their marriage in Vegas. Cristina struggles with giving Burke an answer. Izzie and Bailey start the free clinic.moreless

    Well it appears that Izzie spent her eight million dollars to help open the free Denny memorial clinic at Seattle Grace with Dr. Bailey. I thought it was funny the way she and Alex were tracking down patients and trying to seal them from the E.R. to bring them to the free clinic. So we find out this episode that George and Callie ran off to vegas pretty impulsively and got married. I thought Izzie's comment about small diamonds was hilarious, especially when i saw the way Cristina cracked up and Bailey cut in with "ok, that's it..." George gets reamed out by Callie and learns to stand up for her and for their marriage. Speaking of rings, i can't believe the one Burke gave Cristina. a three carot diamond cut platinum ring. I am so hating Cristina right now. She asked Meredith's mother if you can have both, a life and become a heart surgeon. Grey's mother said she didn't try hard enough herself. Yang eventually says yes to marrying Burke. Backing up a bit, Meredith's mother wound up at the hospital and was completely lucid and had all of her memories back. I thought it was a little harsh the way she reacted to Grey saying she was happy. She basically told her daughter that she was a disappointment. Meredith was a bit harsh back though later on when she went off on her mother. However through all of this Meredith retains some hope about her mother's condition, until she sees her mother at the end of the episode who had relapsed back into her condition of not recognizing her daughter. I feel very bad for Meredith's mother. The chife sort of ruined her. She was so in love with him and wanted him so badly, but he never would have left his wife. She even thinks that she should have fought harder for him when she could have before she got sick. I wonder if she even knows that it was never going to happen because he wouldn't have ever left his wife. He does speak though like he regrets not being with Grey's mother. Whether that's because he's getting divorced now or if he really wishes he could've been with her is another question. So, Addison keeps looking at Alex like a piece of meat. It's a bit funny how she's acting like a love sick school girl. My mouth just about dropped at the end of the episode when she was sleeping with Mark again, and then i realized she was thinking about Alex while she was doing it. The first patient of the free clinic was a little girl who appeared to only need assistance with feminen products and how to use them because she just started her period. However, Bailey is a little shocked when the girl asks if she might be pregnent. Bailey has a heart to heart with the little girl, explaining that if she continues to do the things she's doing, she's going to wind up with an STD or a child or something. Bailey feels pretty good about helping the girl, even though she was the only patient the free clinic got all day. So the hospital had a crisis when a cancer patient's blood turns out to be toxic. The entire team performing her surgery wound up unconscious, and the interns and remaining doctors had to take turns holding their breath and finishing up the procedure by holding their breath and not going in for more than twenty seconds at a time. Mark refuses to go in because of the toxic blood. I did find it a bit humerous when Yang's hand went up and she announced that she could swim three lengths of her parent's pool underwater. Addison takes a heroic risk when she runs in without a protective suit to put the patient back to sleep. I thought the end of the episode was very sad though, when we find Grey's mother has slipped back to her previous condition. When she looked at Grey and said "you remind me of my daughter", i just about cried. This was a great episode.moreless
  • heart breakingly tragic

    oh my god- some parts of this episode are absolutely heart wrenching!!! We see why meredith and her mom dont get on , her mother is unjustifiably cruel, "your ordinary"- how awful for poor mere!! We also see that her mother was a force to be reckoned with and that she "has her ways", shes very manipulative. I reli didnt like the mom, only for the moment when she told christina hat she sud have tried harder to make her marriage wrk and this makes christina say yes to burke.

    On a different note i think everyone was horrible to the newly-weds george nd callie(apart from addison), alex was preti funny tho-"dude, shes callie o' malley!" The storyline with the patient was awesome2!!!!!moreless
  • I loved this of it made me wanna cry but it was an absolutely amazing episode and extremely well written :D

    I don't know where to start with this, the whole episode was amazing and I was totally engrossed from start to finish.

    The trailer from last week's episode made me think that Meredith's mom would die - so it was a great surprise to see that she lives and more than that - she was lucid. I think this episode was unique in that we got to see first hand the relationship between Meredith and her mom and it was absolutely heart-breaking! Meredith had so little time and it was as if she knew it just wouldn't be enough to sort things out. When she argued with her mom and cried and then nearly cried again when she realised after explaining to her mom how she felt at the end of the episode that her mom had no memory again it was so upsetting. I love how the writers can write such a sad episode but still have light-hearted scenes which take the depressing edge off a bit. I was kinda surprised to find out George and Callie were married - in Vegas!?! I had sorta figured she would have been all weird about him asking and gone into one of her weird attitude things so George wouldn't have a clue about where he stood lol.

    The toxic blood thing was kinda funny...but I still jumped outta my skin when I saw all of the surgeons on the floor when George was calling them to tell them about it being toxic - though i have no idea why I was so shocked lol.

    I can't believe Addison is fantasising about Alex so much, maybe it's because he rejected her?! I can obviously see why she wants him- but the woman needs to remain professional!! :p

    So...I guess i've covered the main things - the funniest thing for me was seeing Christina laugh so hard at the end of the episode with Burke, it had me in stitches lol. It's so unusual to see her showing so much emotion!!

    Aside from all of that it was the scenes between Meredith and her mom that really got to mom's gone on vacation and we're sorta not speaking at the moment for the first time ever, but I so appreciate my relationship with her more than I did before (didn't know that was even possible!)...and I will go sort things out with her as soon as she gets back :)moreless
Ellen Pompeo

Ellen Pompeo

Dr. Meredith Grey

Sandra Oh

Sandra Oh

Dr. Cristina Yang

Katherine Heigl

Katherine Heigl

Dr. Isobel "Izzie" Stevens

Justin Chambers

Justin Chambers

Dr. Alex Karev

T.R. Knight

T.R. Knight

Dr. George O'Malley

Chandra Wilson

Chandra Wilson

Dr. Miranda Bailey

Jasmine Di Angelo

Jasmine Di Angelo

Kellie Hansen

Guest Star

Ronobir Lahiri

Ronobir Lahiri

Mr. Hansen

Guest Star

Matt McTighe

Matt McTighe


Guest Star

Kate Burton

Kate Burton

Ellis Grey

Recurring Role

Sarah Utterback

Sarah Utterback

Nurse Olivia Harper

Recurring Role

Kate Anthony (II)

Kate Anthony (II)

Nurse Kate

Recurring Role

Featured Episode Clip

Trivia, Notes, Quotes and Allusions


  • TRIVIA (1)

  • QUOTES (38)

    • Bailey: Kellie, your dad told me that you lost your mother a few years ago, and I want to say how sorry I am. You probably have a million questions, and if your mother were here, I'm sure she would have more eloquent answers than I do. But I actually think that she and I would be saying the same thing, which is that if you keep going the way you're going, you will get an STD. You will get pregnant. You will increase your chances of getting cervical cancer. You're not being smart, and you're too young for anyone to expect you to be smart the way you need to be when you're having sex, which means you shouldn't be having it.
      Kellie (crying): I thought he liked me.
      Bailey: Oh, honey, I know you did. I know you did.

    • Meredith (closing voiceover): When the patient's body has failed them and all the science we have to offer has failed them, when the worst case scenario comes true, clinging to hope is all we've got left.

    • Ellis: Did I have a breakdown? I must have had a nervous breakdown. Is this a hospital? Because I can't remember anything for the past few months. The last thing I remember is the fight we had.. And listen, if you don't want to go to medical school, that is fine. It is your life. Just take me home.
      Meredith: I went to medical school.
      Ellis: I want to go home, Meredith. I need to go home.
      Meredith: You are home. I went to Europe five years ago. You got sick. You have Alzheimer's. This is your home. You live here now.
      Ellis: Noooooo!

    • Richard: I heard you're having surgery tomorrow.
      Ellis: Do you...(pause) Do I know who Meredith is? Do I at least recognize Meredith?
      Richard: You know she is someone important... Someone who loved you.
      Ellis: You'll look out for her... Because she's got so much more to learn and I won't be able to teach her.
      Richard: I'll look out for her.
      Ellis: I wish I could go back... I'd do everything so differently, I'd fight harder for you, I think if I'd fight harder for you maybe... (Richard walks over and sits next to Ellis)
      Richard: We would've have had a wonderful life together Ellis.
      Ellis: You think so?
      Richard: I do, we would have done our fellowship year, and then you would have fought me for chief and probably won (laughs) and, I wouldn't have minded, because we'd have kids and all.
      Ellis: We have kids?
      Richard: Meredith would have needed a brother and sister (pause) kids need family.
      We would have been a family.
      Probably bought that big house on Parker, the one with the barn... Yeah that's a good place for a family.
      Ellis (crying): And I would have been happy, just like Meredith says she's happy and that would have... changed everything... Maybe (sobs) I would be fine and we could grow all together and life would be so perfectly ordinary.
      Yeah. (Ellis is crying. They hold hands)
      My life is so unfinished, it's unfinished, and I'm not finished.
      Richard: No, no, Ellis, don't think that just close your eyes and think of the family... of the house.
      And you there every night to come home to. Richard: And me there... I'm there.

    • (During sex)
      Mark: I thought you said you didn't think about me?
      Addison: I don't. I'm actively not thinking about you. Right. Now.

    • Meredith: The reason that I want you to have the surgery is because I have this hope, that in a year, two years or five, they're gonna have a breakthrough. They're gonna find a cure for Alzhiemer's, and you and I will have another chance. To get to know each other. You'll get a chance to know me, to see that I am not even remotely ordinary, so I wish you would have the surgery. But it's up to you Mom, it's your life.
      Ellis: You remind me of my daughter. (Meredith realizes that her mother is not lucid anymore and tears well up in her eyes)
      Richard: About an hour ago. One minute she was here, the next... I'm so sorry.
      Meredith: Me too. (sighs and leaves)

    • Cristina: I don't do rings. Don't expect me to suddenly change. I'm a surgeon, just like you. And we'll have money, we can hire a wife.
      Burke: Are you saying yes?
      Cristina: Y-yeah.
      Burke: I'm not letting you scrub in tomorrow.
      Cristina: Well, I'm not wearing a ring.
      Burke: Okay.
      Cristina: Okay then.
      Burke: Yes! (Cristina laughs as Burke hugs her in joy)

    • Derek: How come we do all the work and he gets all the glory?
      Addison: Because he's Mark.

    • Meredith: How's George?
      Izzie: Medically he's fine, emotionally he's a little stunted if you ask me. You don't marry the rebound girl. Am I right?
      Cristina: You don't marry anyone on a whim.
      Meredith: No, he needs our support.
      Izzie: He doesn't need us, he's got his Vegas show-wife.
      Cristina: Oh!

    • Callie: Okay, you're gonna live. (walks away)
      George: Callie, wait. (Callie walks back over towards him) I was a little bit heroic in there. I thought you'd be proud of me.
      Callie: Proud? You were poisoned, and you thought it was about me.
      George: It felt like an anxiety attack.
      Callie: About me! You see, we were fine when we were in our Vegas bubble. When-- when it was just room service, and pay cable, and us it was bliss. But you get around your weird and judgey friends for one day and you're racked with uncertainty. Toxic gas level uncertainty. I guess it was too much to hope that you would just stand up for me.
      George: Cal --
      Callie: And my middle name is Iphigenia, okay? I can't wait to hear what your pals have to say about that. (walks away)

    • Richard: Your mother stopped for five years, and you became somethin'.
      Meredith: According to her, I didn't. According to her, I'm a disappointment.
      Richard: In a perfect world, she'd be able to tell you that she was proud of 'ya. But it's not a perfect world and your mother's not a perfect woman.
      Meredith: I think the person that she'd most like to see right now is you.
      Richard: The only thing that your mother wants to hear from me is that I regret staying with Adele. The only gift that I can give to her. And I can't tell her that, it's not true.

    • Ellis: You're good. Sharp under pressure. You'll make an extrodinary surgeon.
      Cristina (long pause): Dr. Grey, I have to ask you. Will it get in my way? Can I have both? Can I be a great surgeon and have a life? Because there's this man who just asked me to marry him and I know you tried to have both but, you split up with Meredith's dad. I know this is none of my business, but --
      Ellis: It is none of your business. (pause) And I didn't try hard enough.
      Cristina: Thank you.

    • Izzie: Stolen, non-emergent ER cases, and sick hospital staff. This is what 8 million dollars buys you.
      Bailey: Dr. Stevens, I swear on my life if I hear you say 8 million dollars one more time...
      Izzie: It's not about the money -- it's -- it's Denny, it's his legacy, I was looking for meaning, this is supposed to be meaningful.
      Bailey: It will be meaningful.
      Izzie: Oh, yeah? 8 million dollars worth?

    • George: I need to lay down.
      Izzie: Whoa, whoa. Hey, hey, buster, do you know how must it costs to -- (George lays down on one of the beds) -- have these linens laundered?
      George: I'm sick. Shakey, sweaty, my mouth is dry, my body aches...
      Izzie (annoyed): Fine.

    • Derek: I just took a special interest in this case ... because of Meredith.
      Ellis: You're what happened to her.
      Derek: I'm sorry ---
      Ellis: I thought you were here for me, to offer me some hope. To tell me about some new treatment, but you're here for her. An attending, a neurosurgeon, no wonder she's so unfocused.
      Derek: I don't think you understand, I --
      Ellis: Oh, I understand. I understand perfectly. I've seen men like you before, threatened by a woman who's their equal. You just want someone to admire you. You don't care about the damage you do to her along the way.

    • (George is breathing hard and sweating)
      Callie: Hey...are you okay? You're sweating. (she goes to feel his temperature with her hand and he bats it away)
      George: What's--what's your middle name?
      Callie: It's bad. I don't tell anyone.
      George: Come on, we're married, and I don't even know your middle name.
      Callie: Okay, I knew it. It's your weird and judgey friends, you let them get to you.
      George: It's just that I don't-- I--I don't know your middle name. God, I can't--I can barely breathe.
      Callie: You know what? You didn't know my middle name last week and you could breathe just fine. (pushes him)

    • Meredith: She's charming, she's fabulous, and suddenly she's the enemy.
      Derek: I'm meeting the enemy?
      Meredith: Just don't get personal.
      Derek: You're being ridiculous.
      Meredith: I'm not being ridiculous.
      Derek: Okay, it's gonna be fine.
      Meredith: Just be careful. She has ways.

    • Meredith: I have a boyfriend.
      Ellis: Does he understand the demands of your career? Because not all men do, they say the do up front but they...
      Meredith: He's great. He's a doctor too, so he gets it.
      Ellis: Good.
      Meredith: He's actually ---
      Ellis: Have you chosen a specialty?
      Meredith: No. It's still early.
      Ellis: Cristina has already chosen cardiothoracics.
      Meredith; Yeah. Well, I guess that I'm just waiting to be inspired. I'm happy now. I feel like I know who I when you have someone in your life that you really love, I think that's ... I don't know. I just -- I'm really happy.
      Ellis: What happened to you?
      Meredith: What do you mean?
      Ellis: You're happy? You're happy now? The Meredith I knew was a force of nature. Passionate, focused, a fighter. What happened to you? You've gone soft! Stammering about a boyfriend and say that you're waiting to be inspired. You're waiting for inspiration? Are you kidding me?! I have a disease for which there is no cure, I think that would be inspiration enough! Listen to me, Meredith. Anyone can fall in love and be blindly happy! But not everyone can pick up a scalpel and save a life. I raised you to be an extraordinary human being, so imagine my disappointment when I wake up after 5 years and discover that you are no more than ordinary! What happened to you?!

    • Cristina: Are you stealing patients from the ER?
      Izzie: Yes. But only because I have to know that I did not spend my entire inheritance on an empty room with empty beds...because if I did that I might go crazy and George called dibs on all the crazy this week. Do you think that Callie's pregnant?

    • Cristina: Hey, Mer. I've been lookin' for you. Burke has me on your mom. Are you okay?
      Meredith: I'm avoiding her. I'm avoiding the gift.
      Cristina: Yeah, well, uh, your gift wants to meet Derek.
      Meredith: What? What did you say?
      Cristina: Not Derek your boyfriend. Dr. Shepherd, the neurosurgeon. She's gonna know that he's your boyfriend, anyway. She has ways. I'm kinda in love with her, by the way.
      Meredith: She has that effect on people, that aren't her daughter.

    • Ellis: You and Meredith are good friends. I can tell...'cause you're afraid to look at me as if I'll ask you some personal question about her and you'll accidentally slip. But you don't do anything accidentally, do you? (Cristina smiles) Has Meredith chosen a specialty?
      Cristina: That's ... a personal question.
      Ellis: For surgeons that's the most personal question you can ask. It tells you who they are.
      Cristina: My mother would want to know if I had a boyfriend.
      Ellis: Your mother sounds like a frivolous woman. (Cristina goes back to doing her paperwork for a moment)
      Cristina: If I chose cardiothoracics, what would that say about me?
      Ellis: Heart surgeons are know-it-alls, they're the most ambitious, the most driven. They want it all and they want it now. And they don't want anything getting in their way.

    • Burke: You're still not wearing the ring. I've been waiting for an answer for over a week.
      Cristina: I told's under advisement.
      Burke: Do you not like the ring?
      Cristina: It's a ring. It's a three karat, diamond cut,'s thee ring.
      Burke: Then what?
      Cristina: Are you using the surgery tomorrow to pressure me into giving you an answer? Is that why I'm not scrubbing in?
      Burke: I've got to give the other interns a chance.
      Cristina: Why?

    • Callie: Okay, we've been out of our Vegas hotel room bubble for six hours and I don't like it.
      George: It's gonna be fine. (kisses her) We're married.

    • Izzie: Okay, where is everybody?
      Bailey: Grey will be late. O'Malley should be back from vacation...
      Izzie: No, no, no. The patients. The under served, uninsured, population that we're supposed to be helping.
      Bailey: The under served, uninsured will come. You'll see. Just watch the door, they will come through it.
      Izzie: I can't wait. I can't wait for the first patient. It's gonna be amazing, it's gonna be amazing what Denny's money can do, right? (Izzie is tapping her fingers anxiously against the counter, Bailey puts her hand on Izzie's to stop her)
      Bailey: Just watch the door, Stevens. (Izzie is focused on the door. Mark and Richard walk in, Izzie pays no attention to them and continues to watch the door)
      Mark: Dr. Bailey, congratulations on the opening of clinic.
      Richard: It is open...isn't it? (looks at Izzie who is still focused on the door) Is Stevens alright?
      Bailey: She's watching the door, sir.

    • Bailey: Welcome to the Denny Duquette Memorial Clinic. Barring any surgical emergencies you'll be working here today.
      Cristina (looking around): Working ... on what?
      Bailey: Right now, Olivia will be familiarizing you on the protocol for the flu vaccine. (Alex is looking at some of the stuff in the clinic)
      Izzie: Oh no, no, no ... don't, don't, don't touch that. That was seventy-nine dollars. (Izzie walks away)
      Cristina: Oh my god, I have got to get out of here.

    • George: People, you're supposed to be my friends. My closest friends. Callie is a big- She's the most important part of my life now. If you wanna drive her away, and you're masters of it, you'll do it. But if she's gone, I'm gone. She's my wife. Calliope Iphigenia Torres is my wife. (sees that Izzie is going to make a snarky remark) Don't you dare.
      Izzie: Okay.

    • George (about the patient): She's toxic.
      Olivia: Callie? Yeah, a lot of us feel that way.

    • Izzie (walks in the room): What's going on?
      Meredith: The chief figured out the anesthesiologist didn't have time to drop an NG tube, so now they have to place one and decompress, and replace her intestines, and close, and they're about to run out of air.
      Izzie: Holy crap. This so beats tampon training.

    • Izzie (taking a deep breath): This is a maxi pad, heavy flow days; mini pad, pretty self explanatory. Just peel the label, and stick it. (demonstrates) And the tampon we've already gone over. So... are we clear on everything? (Kellie glares at Izzie) Kelley, I understand that you're a little mortified that your dad dragged you in here, but can you just talk, or nod, or something?
      Kellie: I get it okay?
      Izzie (under her breath): Great.

    • Meredith: I am not sure refusing treatment is what you want to do.
      Ellis: Apparently what I want doesn't matter it isn't even legally binding so it's really about what you want Meredith. You're in charge.
      Meredith: Do you think I like making these decisions for you. Do you think its fun getting calls from the nursing home asking whether I was planing on giving the nurse who changes you every morning a Christmas tip, but I do it, because you have managed to alienate everybody else in your life, and I am the only one. So I have to step up and do it. You wanna know why I am so unfocused, so ordinary, you wanna know what happened to me, you, you happened to me.
      Ellis: Then let me refuse the heart surgery.
      Meredith: No!
      Ellis: Why not?
      Meredith: Because killing my mother is not going to be another thing that happens to me.

    • (Callie catches Addison staring at Alex as he walked by)
      Callie: Uh, you know those cartoons where there's a bear or whatever and it's starving. And it looks at a table and the table turns into this delicious cooked turkey with like lines of delciousness coming off it.
      Addison: I was not looking at him like that because he is the help and I am not going to be sleeping with the help.
      Callie: I married the help.
      Addison: What?
      Callie: We went to Vegas. My idea. I embrace the trashy.
      Addison: That's -- not that I'm not happy for you. But why - married - so fast?
      Callie: You know those cartoons where there's a bear and it's starving, and it looks at a cute intern.
      Addison: Well, congratulations. (they hug)
      Callie: Thank you. (shows her the ring) It's small. I know it's small.
      Addison: It's beautiful.
      Callie: You think so?
      Addison: Yes.

    • Meredith: You got married?
      George: Yeah, I did. It was uh -- I know it was impulsive.
      Meredith: Well, was it "good" impulsive or "Meredith" impulsive? Because if it was "Meredith" impulsive maybe I can help get you out of it.
      George: No, no it's a good thing. It's good.
      Meredith: Good.
      George: But, uh, thanks for the back up.
      Meredith: You're welcome. Congratulations, George.
      George: Thank you.

    • Izzie (whispering to George): You know, it seems really very fast. Are--are you even happy?
      Callie: We're incredibly happy.
      Izzie: Oh, yay! Well, great! Yay!
      Geroge: Show her the ring.
      Izzie: Oh, that's so great. Tiny diamonds are great because you know no one will ever try to steal it.

    • George (excitedly): We got married in Vegas! We're married! (they are speechless)
      Alex (laughing): Dude, she's Callie O'Malley.

    • Meredith (opening voiceover): As surgeons, we live in a world of worst-case scenarios. We cut ourselves off from hoping for the best because too many times, the best doesn't happen. But every now and then, something extraordinary occurs and suddenly best case scenarios seem possible. And every now and then, something amazing happens and against our better judgement we start to have hope.

    • George: She's toxic, her blood was toxic, it's not our marriage.
      Callie: You thought our marriage was toxic?

    • (After Burke and Derek pass out in surgery because of loss of air)
      Cristina (watching in the gallery with Izzie and Meredith): Well that's not good.

    • (Watching Burke and Derek try to impress the Chief)
      Mark: Aren't you gonna get in there? If you wanna be chief, you've got to fight with the big boys.
      Addison: Oh, I intend to fight like a girl. I'll let them kill each other and then I'll be the only one left standing.
      Mark: And then there's me. (Addison gives him a 'yeah right' look) There you go underestimating me again.
      Addison: Oh, it's not that I underestimate you. It's just that I don't think about you... at all.
      Mark: Well, you should. (walks over to the chief) I was, uh, heading down to the clinic. It's opening today and I thought it might be nice to show Dr. Bailey a little support.
      Chief: Very thoughtful Dr. Sloan. Think I'll join you. Gentlemen, if you'll excuse me.
      Derek: Certainly. (turns to Mark) Nicely done.
      Mark: Uh-hum.

  • NOTES (3)

    • International Titles:
      Czech Republic: Přát si a doufat (Wish and Hope)
      Germany: Toxisch (Toxic)

    • Original International Air Dates:
      The Netherlands: April 9, 2007 on Net 5
      Italy: May 7, 2007 on Foxlife
      New Zealand: May 10, 2007 on TV2
      Australia: June 3rd, 2007 on Channel 7
      Switzerland: June 2, 2007 on SF 2
      Israel: June 11, 2007 on Yes Stars 1
      Germany: September 12, 2007 on Pro 7
      Ireland: September 11, 2007 on RTÉ Two
      South Africa: September 17, 2007 on Mnet
      Norway: November 13, 2007 on TV2
      Finland: November 28, 2007 on Nelonen
      Croatia: December 10, 2007 on NOVA TV
      Romania: April 22, 2008 on TVR1

    • Music Featured In This Episode:
      1. Elevator Music by Beck
      2. King of You by Psapp
      3. Fireworks by The Whitest Boy Alive
      4. Canal Song by Iain Archer
      5. Barracuda by Miho Hatori
      6. Runaway by Sybarite featuring Psapp
      7. Believer by Susanna And The Magical Orchestra
      8. Make This Go On Forever by Snow Patrol


    • Episode Title: Wishin' and Hopin'

      This is the title of a song by Dusty Springfield. It has also been recorded by artists such as Ani DiFranco and Dionne Warwick.