Amanda attempts to stop the Immortal Sean from taking revenge on Liam, another Immortal who has forsworn violence and become a priest. Meanwhile, Nick and Amanda deal with a reporter who has seen Amanda come back to life.
Nick's ex-wife, Lauren, is unwittingly on the trail of an Immortal who is using his medical center to cover a bootleg organ operation. When Nick discovers she's in Paris, they rekindle their romance.
Amanda and Nick go after a casino thieve and discover the leader is Jeremy Dexter, Amanda's former Immortal partner. Nick and Amanda disagree on what to do about Jeremy, and things become tense when Nick teams up with an Interpol agent seeking revenge on Dexter.
Nick and Bert Myers go after a kidnapper, Markham, and discover that he's an Immortal who forced Amanda to marry him a century ago to prevent her from testifying against him.
An Immortal, Jade, arrives to continue her century-old rivalry with Amanda by one-upping her and performing even more risky thefts. However, when she steals a painting and frames Amanda, Nick discovers that the painting is a fake, and the owner plans to collect the insurance.
Nick and Amanda become involved in the theft of a viral plague from a chemical plant. They soon discover that Talia, an Immortal, is involved with the plant's owner and claims the plague is a derivative of her blood which will give humans immortality.
A ruthless Immortal, Andre Korda, once forced Amanda to train with him. In the present, the Watchers are trying to find Korda after he robbed an armored car, which puts Nick on his trail.
An Immortal, Victor Hanson, discredits and then murders a friend of Nick's as the first step in his plan to steal a valuable diamond. For his next step, he wants to seduce Amanda into helping him.
Lucy goes after an Immortal actor, Wilson Geary, to get revenge on the death of her husband Marco... another Immortal. However, Geary claims that Lucy seduced him. Amanda must find out the truth and keep Lucy alive.
Bert Myers tries to recruit Amanda to steal files from a man, without revealing that the files can be used to blackmail him. Bert ends up killing the man, Ludwig, but the man's assistant has the files and uses them to force Bert to commit an assassination.
An Immortal soldier seeks revenge on the people he holds responsible for the death of his mortal comrades in the Gulf War due to friendly fire. When he discovers that Amanda inadvertently played a role in their deaths, she becomes his next target.
Nick goes after a former ex-ballplayer turned murderer, who the authorities believe is responsible for the recent death of a DA. However, Nick soon discovers that the killer may have been set up for both murderer, and asks Amanda to go undercover as a blackmailer to get the evidence he needs to convict the real killer.moreless
Amanda tries to avenge the death of a thief who was trying to recover a deed that freed his ancestors from slavery, but the police suspect that she and Nick are responsible.
Amanda comes to the aid of an old mortal friend, Charlie, who is seeking revenge for the death of his son, a scientist working on a secret agricultural project for the government.
Nick needs help from Amanda to get the goods on Marta, a killer using diplomatic immunity to avoid capture. However, Amanda is busy dealing with an obsessed Immortal, Stefan Collier. She agrees to help Nick to distract her from Collier.
Nick is hired to provide security for the head of a telecommunications empire, and narrowly keeps the CEO from being assassinated. Amanda realizes that an Immortal friend is responsible and tries to keep Nick from going after the man and being killed.
The Immortal thief, Amanda, sets out to discover who killed her fence. Meanwhile, police detectives Nick Wolfe and Claudia Hoffmann follow her. However, they soon discover that a crooked detective, Stanley Ferris, is responsible for the murder and trying to frame Amanda for the crime.