Bill Macy was previously seen in the season 2 episode, 'Cindy.'
John Pleshette appeared as a different character in the season 3 episode 'All That Glitters.'
Bob Hope is a special guest star in this episode.
Will Estes has a role in the season 5 episode 'Merry Christmas from Grandpa.'
Dorothy McGuire previously portrayed Jonathan's wife Jane in the season 2 episode Keep Smiling.
Byron Thames appeared on Landon's other program, 'Father Murphy,' in the featured role of Matt Sims.
Michael Faustino, brother of actor David Faustino, would again work with Landon in the made-for-TV movie Where Pigeons Go To Die.
Darlene Conley appeared in a season eight episode of 'Little House' called 'A Wiser Heart.'
Richard Farnsworth appeared in the season 3 episode of 'Little House' entitled 'Quarantine.'
Guest Bruce French would be cast in Landon's TV-movie Where Pigeons Go To Die.
This is not the first time Landon has used the series as a platform to tell the stories of the handicapped. In season one, quadriplegic James Troesch appeared in three episodes. In both cases, Landon allowed these men to take a part in the development of scripts that used elements from their own lives.
Tom Sullivan reprises the role of Frank in season 5's episode Summer Camp.
Eric Douglas was the son of Kirk Douglas. His character's name is taken from GONE WITH THE WIND: it's a combination of the character Rhett Butler and actor Clark Gable.
In the scene where Jonathan and Mark are driving along, Jonathan reminds Mark that it was a year ago that he faced the devil. The writers got that wrong. It wasn't a year ago, it was more like two years ago. It was back in season 2, The Devil and Jonathan Smith. Also the actor that is playing the big kid whose being a prisoner and said that our father is a dentist, is Ian Petrella from the famous Christmas movie, A Christmas Story. He played Ralphie's little brother,Randy.
In this episode, Victor French's charter Mark mentions his snake ball pitch which is the same pitch he was talking about in the Little House show, Look Back to Yesterday at the baseball game played at the Wilder's.
John Lawlor appeared in the season 1 episode 'One Winged Angels' in a different role.
Richard Bergman appeared on 'Father Murphy' in the recurring role of Father Joe Parker.
Danny Pintauro is best known as "Jonathan" on TV's WHO'S THE BOSS. His film credits include the horror epic CUJO.