An old friend gives Mary-Claire a fresh perspective on her relationship with Harry. Jonny tries to help a grieving mother do the right thing after the tragic death of her son. Sacha tries to bond with Rachel again, but the results are nothing short of disastrous.
Sacha struggles to be a good father to Rachel in the face of a major revelation. Mo tries to hide from Adele, not ready to tell her about the family secret. Mary-Claire, desperate to deny her feelings for Harry, tries keeping him at arm's length.
Jac considers the possibility of a new start with Emma in the USA. Sacha is shocked when his daughter is admitted into Holby. Sparks fly between Harry and Mary-Claire. Was their New Year assignation really a one-off?
Elliot's plans for a quiet family Christmas are derailed by the arrival of a friend in need. Arthur must step up when those around him are falling apart. Ric returns to AAU and manages to tread on quite a few toes.
Zosia gets emotionally involved with a patient with catastrophic consequences. Mo has a new lease of life when she is advised to follow her heart. Serena acts the fairy godmother to Amy, Raf and Harry as they wait for baby Callum's paternity results.
Raf is thrown when Amy has an unexpected request. With LA firmly in his sights, Dominic ruthlessly risks all to fulfil his ambitions. It's secret santa and as Mo plays detective, has she found her perfect man?
Jesse is forced to face up to how his dalliance with Zosia may have impacted her health. Zosia fights to prove to herself that her medication doesn't affect her abilities. Serena has to aggressively defend AAU from cuts imposed by the Holby board.
Guy is forced to confront the fact that Zosia may not be cured of her mental illness. Elliot completes the design for his new device and has to fight for funding to build a prototype. Raf tries to support an unemotional Serena on the day of her mother's funeral.
Colette's loyalties are tested as her struggle to help Zosia pushes her relationship with Guy to breaking point. Is it time for Colette to spread her wings? Raf's clumsy foray into dating leads to calamity on the ward and lands him in hot water with Michael. Adele is less than impressed with Jesse's slick charm, but is there more to him than meets the eye?moreless
Mo is determined to prove she can swim with the sharks, but is she in over her head? Serena's personal and professional lives collide when her mother is brought in for treatment. The knives are out on Keller as Sacha and Fleur battle for supremacy.
When Raf is confronted with a patient needing complex specialist surgery, Fletch wonders if he will put his feud with Harry behind him and step up to the plate. Guy needs to get on Jac's good side to placate a dignitary from a valued fundraising organisation. A misunderstanding leads to Dom calling Kyle's loyalty towards him into question.moreless
Raf needs to step up his game on AAU, while Michael Spence is back in town. New consultant Fleur Fanshawe shakes things up on Keller, leaving Sacha feeling undermined. Jac detaches herself emotionally even further from her daughter.
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