Hollywood Animal Crusaders chronicles the activities of Last Chance for
Animals, a group of individuals who saves animals. They get a lot of
support for their advocacy from Hollywood A-listers like John Travolta,
Cher, Bret Michaels and Don Johnson. The group led by animal rights
advocate Chris de Rose are shown monitoring investigations of animal
cruelty cases, dealing with pet theft, illegal animal slaughter, and pet
neglect. Other members of the group include Esai Morales, Rikki
Rockett, and Greg Louganis.